ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Apical

Proteins in this localisation are known in Plasmodium falciparum, Plasmodium knowlesi, Plasmodium yoelii, Plasmodium berghei, Plasmodium vivax, Toxoplasma gondii, Babesia bovis, Neospora caninum, Cryptosporidium parvum, Theileria parva, Plasmodium gallinaceum, Babesia gibsoni, Sarcocystis neurona, Eimeria tenella.

This specific localisation comes under the apical umbrella.

There may also be proteins excluded from this location, i.e. not apical

Plasmodium falciparum

Also known as anterior, apex, apical cap, apical foci, apical tip, crescent shaped cap associated with apical pole, widely distributed in apical. View all proteins localised in Plasmodium falciparum.

  • PF13_0233 (MyoA, -myo1) myosin A
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • PF11_0486 (MAEBL) merozoite adhesive erythrocytic binding protein
  • PFF1370w (PK4) protein kinase PK4
  • PF14_0102 (RAP-1 p86, RAP-1 p82, RAP-1 p67, RAP1, RAP-1) rhoptry-associated protein 1
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • PF11_0381 (SUB2) subtilisin-like protease 2
  • PFL0870w (PTRAMP) thrombospondin-related apical membrane protein
  • MAL13P1.176 (RpfR2Ha, RBP-Hb, Rh2b, NBP2b) reticulocyte binding protein 2 homologue b
  • PF13_0198 (RpfR2Hb, RBP-Ha, Rh2a, NBP2a) reticulocyte binding protein 2 homologue a
  • PFE0395c (Pf38) 6-cysteine protein
  • PFD0240c ( 41, Pf41) 6-cysteine protein
  • PFD0110w (NBP-1, Rh1) normocyte binding protein 1,reticulocyte binding protein homologue 1
  • MAL7P1.176 (EBA-175, EBA175) erythrocyte binding antigen-175
  • No assigned gene identifier (EBL-1)
  • MAL7P1.119 (RALP1) rhoptry-associated leucine zipper-like protein 1
  • PFE0175c (MyoB) myosin B
  • PFD1150c (RH4) reticulocyte binding protein homologue 4
  • PF11_0139 (PRL, EP) protein tyrosine phosphatase
  • PFC0110w (CLAG 3.1, RhopH1 3.1, Clag3.1) cytoadherence linked asexual protein 3.2
  • PFD1145c (Rh5, RH5) reticulocyte binding protein homologue 5
  • PF14_0495 (RON2) rhoptry neck protein 2
  • PFB0680w (RON6) rhoptry neck protein 6
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • PFE1545c (Formin1) formin 1, putative
  • PF08_0108 (PM X) plasmepsin X
  • PFD0230c dipeptidyl peptidase 3
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PFD1105w (AARP) asparagine-rich protein
  • PFD1130w conserved Plasmodium protein, unknown function
  • PF10_0119 conserved Plasmodium protein, unknown function
  • PF10_0166 conserved Plasmodium protein, unknown function
  • PF10_0295 conserved Plasmodium protein, unknown function
  • PF14_0119 p1/s1 nuclease, putative
  • PF14_0572 conserved Plasmodium membrane protein, unknown function
  • PFL0300c protein phosphatase, putative
  • MAL13P1.94 conserved Plasmodium membrane protein, unknown function
  • PFD0720w conserved ARM repeats protein, unknown function
  • PF10_0156 conserved Plasmodium protein, unknown function
  • PF10_0223 conserved Plasmodium membrane protein, unknown function
  • PFL2085w conserved Plasmodium protein, unknown function
  • PF13_0125 conserved Plasmodium protein, unknown function
  • PFB0475c conserved Plasmodium protein, unknown function
  • PFD0705c conserved protein, unknown function
  • PFI1015w conserved Plasmodium protein, unknown function
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PFI0880c (GAP50, SAP) glideosome-associated protein 50,secreted acid phosphatase

Plasmodium knowlesi

View all proteins localised in Plasmodium knowlesi.

  • PKH_041310 (MSP-5, MSP5) merozoite surface protein 5

Plasmodium yoelii

View all proteins localised in Plasmodium yoelii.

  • PY02159 (P140, RON4) Drosophila melanogaster CG15040 gene product
  • PY04858 (CTRP) ookinete protein-related
  • PY04986 (USO3) 250-270 copies of a 13 AA repeat, NSSTPITSSSIL
  • PY03052 (TRAP) sporozoite surface protein 2 precursor
  • PY07092 (TRSP) hypothetical protein
  • PY00204 (S3, UIS4) hypothetical protein
  • PY03011 (S7) early transcribed membrane protein family
  • PY01365 (PY01365) rhoptry protein
  • PY04764 (EBL) duffy receptor, beta form precursor

Plasmodium berghei

Also known as apical tip. View all proteins localised in Plasmodium berghei.

Plasmodium vivax

View all proteins localised in Plasmodium vivax.

Toxoplasma gondii

Also known as apical end, focus at apex. View all proteins localised in Toxoplasma gondii.

Babesia bovis

View all proteins localised in Babesia bovis.

Neospora caninum

Also known as apical complex. View all proteins localised in Neospora caninum.

Cryptosporidium parvum

View all proteins localised in Cryptosporidium parvum.

  • cgd6_4840 (SUB1) serine protease, subtilase family, signal peptide
  • cgd1_3500 (TRAP-C1) thrombospondin related adhesive protein
  • cgd6_5410 (CP2) signal peptide plus thr stretch, charged repeats, likely mucin
  • cgd7_1730 (a135) CpCCp1/Cpa135
  • cgd2_70 (ABC2) ABC transporter, with 12 x transmembrane domains and 2x AAA domains
  • cgd1_700 (ABC, ABC1) ATP-binding cassette protein
  • cgd4_2720 (ATPase1) P-type ATpase involved in cation transport
  • cgd6_1080 (gp40/15, gp15, gp-15, GP15, GP40, gp40) conserved hypothetical protein
  • cgd4_2330 (CP12) hypothetical protein
  • cgd6_2330 (p30) hypothetical protein with signal peptide

Theileria parva

View all proteins localised in Theileria parva.

Plasmodium gallinaceum

View all proteins localised in Plasmodium gallinaceum.

Babesia gibsoni

View all proteins localised in Babesia gibsoni.

  • DQ386864 (RAP-1a) gi|88770793|gb|DQ386864.1| Babesia gibsoni rhoptry-associated protein mRNA, complete cds
  • AB480715 (RAP-1b) gi|255708245|dbj|AB480715.1| Babesia gibsoni BgRAP-1b mRNA for rhoptry-associated protein-1b, complete cds
  • AB480716 (RAP-1c) gi|255708247|dbj|AB480716.1| Babesia gibsoni BgRAP-1c mRNA for rhoptry-associated protein-1c, complete cds

Sarcocystis neurona

View all proteins localised in Sarcocystis neurona.

  • AY325815 (NTP1) gi|32816823|gb|AY325815.1| Sarcocystis neurona nucleoside triphosphate hydrolase (NTP) mRNA, complete cds

Eimeria tenella

Also known as apex. View all proteins localised in Eimeria tenella.

  • AJ306453 (MIC4) gi|187340650|emb|AJ306453.2| Eimeria tenella mRNA for microneme protein 4 (mic4 gene)
  • EU093966 (MIC1) gi|156257451|gb|EU093966.1| Eimeria tenella microneme 1 precursor, mRNA, partial cds
  • AJ245536 (MIC5) gi|5708121|emb|AJ245536.1| Eimeria tenella mRNA for microneme protein 5 (mic-5 gene)
  • Z71755 (MIC2) gi|209414697|emb|Z71755.2| Eimeria tenella mRNA for acidic microneme protein precursor, clone Etmic-2
  • AY512381 (MIC3) gi|40549146|gb|AY512381.1|AY512381S1 Eimeria tenella microneme protein MIC3 gene, partial cds
  • AF042329 (Hsp90) gi|2792526|gb|AF042329.1| Eimeria tenella heat shock protein 90 (hsp90) mRNA, complete cds
  • AF353515 (Enolase) gi|13774514|gb|AF353515.1| Eimeria tenella enolase mRNA, complete cds
  • AF043910 (PYK) gi|2854032|gb|AF043910.1| Eimeria tenella pyruvate kinase (PYK) mRNA, complete cds