ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Specifically localised during 'trophozoite'

Proteins expressed during this time are known in Plasmodium falciparum, Plasmodium yoelii, Plasmodium berghei, Plasmodium vivax, Toxoplasma gondii, Babesia bovis, Cryptosporidium parvum, Plasmodium gallinaceum, Babesia microti.

This specific developmental stage comes under the trophozoite umbrella.

Plasmodium falciparum

Also known as asexual stages, blood stages, erythrocytic stages, troph, trophozoites, trophs.

  • PF10_0168-b (GRASP, GRASP1) golgi re-assembly stacking protein 1
  • PFD0810w (Sar1p, Sar1) small GTP-binding protein sar1
  • PFD0895c (Bet3p) Bet3 transport protein, putative
  • PF11_0461 (Rab6) Rab GTPase 6
  • PF13_0280 (ERD2) ER lumen protein retaining receptor
  • PF11_0171 (Sec12) ER membrane protein Sec12
  • PF13_0324 (Sec24a) Sec24 subunit a
  • PFI0875w (grp, Hsp70-2, BiP) heat shock protein 70
  • MAL13P1.231 (Sec61) Sec61 alpha subunit, PfSec61
  • MAL7P1.27 (CRT) chloroquine resistance transporter
  • PFE0065w (SBP1, SBP) skeleton-binding protein 1
  • MAL7P1.231 (HRPII, hrp2, pfhrp2, hrpII) histidine-rich protein II
  • PF14_0076 (FAF-2, aspartic hemoglobinase I, PMI, PM1, Plasmepsin I, PM I) plasmepsin I
  • PF14_0077 (PM II, PM2, PMII, Plasmepsin II) plasmepsin II
  • PF14_0078 (HAP) plasmepsin III,histo-aspartic protease
  • PF14_0075 (PM IV, PM4) plasmepsin IV
  • PF13_0133 (PM V, PM5, PMV) plasmepsin V
  • PF14_0281 (PM IX) plasmepsin IX
  • PF08_0108 (PM X) plasmepsin X
  • MAL13P1.413 (MAHRP-1, MAHRP1, MAHRP) membrane associated histidine-rich protein
  • PFI1735c (REX1) ring-exported protein 1
  • PFL1960w (EMP1) erythrocyte membrane protein 1, PfEMP1
  • PF11_0165 (Falcipain-2, FP2) cysteine proteinase falcipain 2a
  • PFL1465c (HslV) heat shock protein hslv
  • PFC0890w (Sec22) SNARE protein
  • MAL13P1.169 (Syn5p) syntaxin, Qa-SNARE family
  • PFI1195c (TPK) thiamine pyrophosphokinase
  • PF13_0322 (FLN) falcilysin
  • PFB0385w (ACP) acyl carrier protein
  • PF10_0153 (Cpn60, Hsp60, hsp60) heat shock protein 60
  • MAL13P1.220 (LipA) lipoate synthase, putative
  • PF13_0083 (LplA) lipoate protein ligase a type 1
  • PFL2210w (ALAS) delta-aminolevulinic acid synthetase
  • PF14_0381 (PGBS, ALAD) delta-aminolevulinic acid dehydratase
  • PFL0480w (HMBS, PBGD) porphobilinogen deaminase
  • PF14_0382 (SPP) stromal-processing peptidase, putative
  • PF14_0541 (VP1, V-type H(+)-translocating pyrophosphatase) V-type H( )-translocating pyrophosphatase, putative
  • PFC0525c (GSK-3) glycogen synthase kinase 3
  • PF11_0506 (Pf332) antigen 332, DBL-like protein
  • PF11_0301 (SPDS) spermidine synthase
  • PF13_0252 (NT1, ENT1) nucleoside transporter 1
  • PF14_0679 (SulP) inorganic anion exchanger, inorganic anion antiporter
  • PFL1420w (MIF) macrophage migration inhibitory factor
  • PFI0450c (ARP) apoptosis-related protein, putative
  • PFI0050c (RIFIN) rifin
  • MAL13P1.225 (Trx2) thioredoxin 2
  • MAL13P1.214 (pmt) phosphoethanolamine N-methyltransferase
  • PF11_0396 (PP2C) protein phosphatase 2c
  • PFL0620c (Gatp) glycerol-3-phosphate acyltransferase
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • MAL7P1.150 (IscS) cysteine desulfurase, putative
  • PFL1545c (Cpn60-2) chaperonin, cpn60
  • PF08_0066 (aLipDH) lipoamide dehydrogenase
  • PFL1550w (mLipDH) lipoamide dehydrogenase
  • PF11_0061 (H4, h4k5ac, H4K5Ac, H4K8Ac, H4Ac4) histone H4
  • PFE0150c (IspE) 4-diphosphocytidyl-2c-methyl-D-erythritol kinase (CMK), putative
  • PF10_0218 (CS, CSP, citrate synthase) citrate synthase, mitochondrial precursor, putative
  • PFC0380w (YVH1) dual specificity phosphatase
  • PF11_0098 (ERC, ERC1, Pfs40, Pf39) endoplasmic reticulum-resident calcium binding protein
  • PFB0095c (EMP3) erythrocyte membrane protein 3
  • PFB0100c (KAHRP, HRP1) knob-associated histidine-rich protein
  • PFF1105c (chorismate synthase, CS) chorismate synthase
  • MAL13P1.185 (PK6) protein kinase 6
  • PFA0410w (ARP) conserved Plasmodium protein, unknown function
  • PF14_0761 (ACS1) acyl-CoA synthetase
  • PFI1260c (HDAC1) histone deacetylase
  • PFF1370w (PK4) protein kinase PK4
  • MAL13P1.279 (PK5, CDPK5) protein kinase 5
  • PFE0040c (MESA, EMP2) mature parasite-infected erythrocyte surface antigen,erythrocyte membrane protein 2
  • PFF0995c (MSP-10) merozoite surface protein 10
  • PFL1385c (ABRA, MSP9, MSP-9) merozoite surface protein 9
  • PF13_0348 (Rhop148) rhoptry protein
  • PFE0120c (MSP-8) merozoite surface protein 8,ring-stage membrane protein 1
  • PFL0150w (Orc1, ORC1) origin recognition complex subunit 1
  • PF13_0152 (Sir2) transcriptional regulatory protein sir2a
  • PFF0530w (Tk) transketolase
  • PFL1315w (K1, pfkch1) potassium channel protein
  • PF11_0162 (Falcipain-3, FP3) cysteine proteinase falcipain 3
  • PFL0145c (HMGB1) high mobility group protein
  • MAL8P1.72 (HMGB2) high mobility group protein
  • PFE1195w (Kb) karyopherin beta
  • PFL0565w (j4) heat shock protein DNAJ homologue Pfj4
  • PF08_0054 (hsp, Hsp70-1) heat shock protein 70
  • PFI0930c (NAPS, NapS) nucleosome assembly protein
  • PFL0185c (NAPL) nucleosome assembly protein
  • PFL2275c (FKBP35) FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
  • PF08_0129 (CnA) serine/threonine protein phosphatase, putative
  • PF13_0080 (TERT) telomerase reverse transcriptase, putative
  • PF14_0068 (Nop1) fibrillarin, putative
  • PF11_0174 (DPAP1) cathepsin C, homolog,dipeptidyl peptidase 1
  • PF14_0548 (Vps4) ATPase Vps4, putative
  • PFI1370c (PSD) phosphatidylserine decarboxylase
  • PF11_0224 (exp-1, EXP1, EXP-1) circumsporozoite-related antigen
  • PFL1620w (AARP1) asparagine and aspartate rich protein 1
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PF10_0159 (GBP130) glycophorin binding protein
  • PFA0110w (RESA) ring-infected erythrocyte surface antigen
  • PF11_0302 (PV-1) parasitophorous vacuolar protein 1
  • PF14_0678 (EXP2, EXP-2) exported protein 2
  • MAL13P1.122 (SET2) SET domain protein, putative
  • PF13_0293 (SET6) histone-lysine N-methyltransferase, putative
  • PFL0575w (LSD1) lysine-specific histone demethylase 1, putative
  • PFL1010c conserved Plasmodium protein, unknown function
  • PF08_0012 (KMT1, SET3) SET domain protein, putative
  • PFE0285c (SUMO) small ubiquitin-related modifier, putative
  • PFL0040c (FIKK12) serine/threonine protein kinase, FIKK family
  • PFD1165w (FIKK4.1) serine/threonine protein kinase, FIKK family
  • PFI0105c (FIKK9.3) serine/threonine protein kinase, FIKK family
  • PFI0120c (FIKK9.6) serine/threonine protein kinase, FIKK family
  • PFI0100c (FIKK9.2) serine/threonine protein kinase, FIKK family
  • PF11_0139 (PRL, EP) protein tyrosine phosphatase
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • PF14_0016 (SEP14) early transcribed membrane protein 14.1
  • PF11_0040 (SEP11.1) early transcribed membrane protein 11.2
  • PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4
  • PFC0435w parasite-infected erythrocyte surface protein
  • PFI1160w (LplA2) lipoate protein ligase a type 2
  • PFB0505c (FabH) beta-ketoacyl-ACP synthase III
  • PFF1130c (SOD2) superoxide dismutase
  • PFB0680w (RON6) rhoptry neck protein 6
  • PFL1005c (HP1, H1) heterochromatin protein 1
  • PF14_0242 (PRMT1) arginine methyltransferase 1
  • PFI0735c (NDH) type II NADH:quinone oxidoreductase
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PF14_0498 (sDer1-1, Der1-Pl) DER1-like protein
  • PF14_0653-a (hDer1-1) derlin-1
  • PF14_0653-b derlin-1
  • PF13_0182 (sUba1) ubiquitin-activating enzyme
  • PFE1460w (Tic22) apicoplast TIC22 precursor
  • PFL0925w (Formin2) formin 2, putative
  • PF14_0344 (PTEX150) translocon component PTEX150
  • PF11_0175 (HSP101, ClpB2) heat shock protein 101
  • PFD1110w (GAPM2) glideosome associated protein with multiple membrane spans 2
  • PFL1090w (GAP45) glideosome-associated protein 45
  • PF14_0294 (map-1) mitogen-activated protein kinase 1
  • PF14_0517 (APP) aminopeptidase P
  • PFI0550w (CRMP1) cysteine repeat modular protein 1
  • PFC0140c (NSF) N-ethylmaleimide sensitive fusion protein, putative
  • PF13_0328 (PCNA, PCNA1) proliferating cell nuclear antigen
  • PFB0720c (ORC5) origin recognition complex subunit 5
  • PF10_0155 (enolase) enolase
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • PFE1150w (Pdh1, mdr1) multidrug resistance protein
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PFL1410c (MRP2) ABC transporter, (CT family)
  • PF13_0218 (MDR5) ABC transporter (MDR family), putative
  • PFD0255w (mag-1) ag-1 blood stage membrane protein homologue
  • PFB0540w (H4K20me3) conserved Plasmodium protein, unknown function
  • MAL7P1.91 (FEST) exported serine/threonine protein kinase
  • MAL13P1.310 (calpain) calpain
  • PF14_0020 (CK) choline kinase
  • PF11_0257 (EK) ethanolamine kinase, putative
  • PF14_0368 (TPx-1) thioredoxin peroxidase 1
  • PF08_0131 (1-Cys-Prx) 1-cys peroxiredoxin
  • PFL0725w (pftrx-px2, TPx-2) thioredoxin peroxidase 2
  • PFA0330w (AARP2) small ribosomal subunit assembling AARP2 protein
  • PFL1480w (Sec13p) protein transport protein Sec13, putative
  • PFI1755c (REX3, Rex3) ring-exported protein 3
  • PF11_0145 (GloI) glyoxalase I
  • PFD0311w (cGloII) cytosolic glyoxalase II
  • PFL0285w (tGloII) targeted glyoxalase II
  • PF13_0229 (IRPa) aconitase
  • PF10_0164 (ETRAMP10.3) early transcribed membrane protein 10.3
  • PF10_0141 (mrk) MO15-related protein kinase
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PFF0510w (H3, h3k9m3, h3k9ac, H3K9Me1, H3K9me3, H3K9ac) histone H3
  • MAL8P1.32 (NT2) nucleoside transporter 2
  • PFD0462w (j1, DnaJA) heat shock protein 40
  • PFC0310c (ClpP) ATP-dependent Clp protease proteolytic subunit
  • PF13_0353 NADH-cytochrome b5 reductase, putative
  • PFL1555w cytochrome b5, putative
  • PFF0170w (CHA) cation/H antiporter
  • PFE0435c (SSB) single-strand binding protein, putative
  • PF13_0276 (MAHRP2) membrane-associated histidine rich protein 2, (MARHP2)
  • PFC1050w (TSN, Tudor-SN) survival of motor neuron (SMN)-like protein
  • PF08_0036 (Sec23) Pfsec23
  • PF08_0071 (SOD1) Fe-superoxide dismutase
  • PF14_0177 (MCM2) minchromosome maintenance (MCM) complex subunit
  • PF13_0291 (MCM6) minchromosome maintenance (MCM) complex subunit
  • PFB0345c (SERA4, SERA3) serine repeat antigen 4
  • PFB0340c (SERA5, SERP, p126, SERA, pl26) serine repeat antigen 5
  • PFB0335c (SERP H, SERA6, SERP-H) serine repeat antigen 6
  • PFI0265c (RhopH3, Rhop-3) high molecular weight rhoptry protein 3
  • PFL1700c (VP1) V-type K -independent H -translocating inorganic pyrophosphatase
  • PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative
  • PFE0160c (SR1) Ser/Arg-rich splicing factor, putative
  • PF10_0168-a (GRASP2) golgi re-assembly stacking protein 2
  • PFI0515w (Ykt6.1) SNARE protein, putative
  • PFB0200c (AspAT) aspartate aminotransferase
  • PF14_0534 (SHMTm) serine hydroxymethyltransferase, putative
  • PF10_0268 (MCP-1, nPrx) merozoite capping protein 1
  • PF13_0095 (MCM4) minchromosome maintenance (MCM) complex subunit, putative
  • PF14_0408 (SRPK2, CLK-2) serine/threonine protein kinase, putative
  • MAL13P1.274 (PP5) serine/threonine protein phosphatase
  • PF14_0025 (Rpn6) proteosome subunit, putative
  • PFC0920w (H2A.Z) histone H2A variant, putative
  • PF10_0026 (PArt) tryptophan-rich antigen 3
  • PF14_0641 (Dxr) 1-deoxy-D-xylulose 5-phosphate reductoisomerase
  • PFF0860c (H2A) histone H2A

Plasmodium yoelii

  • PY06203 (pypAg-1) blood-stage membrane protein Ag-1
  • PY06415 (pAg-2) merozoite surface protein precursor
  • PY00414 (2-Cys Prx) thioredoxin peroxidase 1
  • PY04285 (1-Cys Prx) 1-cys peroxidoxin

Plasmodium berghei

Also known as troph, trophs.

Plasmodium vivax

Also known as all rbc stages, rbc stages.

Toxoplasma gondii

Babesia bovis

Also known as ring, ring stage.

Cryptosporidium parvum

  • cgd6_5410 (CP2) signal peptide plus thr stretch, charged repeats, likely mucin

Plasmodium gallinaceum

Also known as troph.

  • DQ068022 (SES) gi|68521875|gb|DQ068022.1| Plasmodium gallinaceum SES mRNA, complete cds

Babesia microti

Also known as ring form.