ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Specifically localised during 'schizont'

Proteins expressed during this time are known in Plasmodium falciparum, Plasmodium yoelii, Plasmodium berghei, Plasmodium vivax, Toxoplasma gondii, Theileria annulata, Theileria parva, Plasmodium gallinaceum, Eimeria tenella.

This specific developmental stage comes under the schizont umbrella.

Plasmodium falciparum

Also known as asexual stages, blood stages, daughter merozoite formation, dividing troph, erythrocytic schizont, erythrocytic stages, mature, mature intraerythcytic, schizonts.

  • PF10_0168-b (GRASP, GRASP1) golgi re-assembly stacking protein 1
  • PFD0810w (Sar1p, Sar1) small GTP-binding protein sar1
  • PFD0895c (Bet3p) Bet3 transport protein, putative
  • PF11_0461 (Rab6) Rab GTPase 6
  • PF11_0171 (Sec12) ER membrane protein Sec12
  • PF13_0324 (Sec24a) Sec24 subunit a
  • PFI0875w (grp, Hsp70-2, BiP) heat shock protein 70
  • PFB0640c (Sec31, Sec31p) sec31p
  • PF13_0280 (ERD2) ER lumen protein retaining receptor
  • PFI0880c (GAP50, SAP) glideosome-associated protein 50,secreted acid phosphatase
  • PFL1090w (GAP45) glideosome-associated protein 45
  • PF10_0281 (MTRAP) merozoite TRAP-like protein
  • PFB0340c (SERA5, SERP, p126, SERA, pl26) serine repeat antigen 5
  • PF14_0102 (RAP-1 p86, RAP-1 p82, RAP-1 p67, RAP1, RAP-1) rhoptry-associated protein 1
  • MAL13P1.231 (Sec61) Sec61 alpha subunit, PfSec61
  • MAL7P1.27 (CRT) chloroquine resistance transporter
  • PFE0065w (SBP1, SBP) skeleton-binding protein 1
  • MAL13P1.413 (MAHRP-1, MAHRP1, MAHRP) membrane associated histidine-rich protein
  • PFL1465c (HslV) heat shock protein hslv
  • PFC0890w (Sec22) SNARE protein
  • PF13_0322 (FLN) falcilysin
  • PFB0385w (ACP) acyl carrier protein
  • PF10_0153 (Cpn60, Hsp60, hsp60) heat shock protein 60
  • PFL2210w (ALAS) delta-aminolevulinic acid synthetase
  • PF14_0381 (PGBS, ALAD) delta-aminolevulinic acid dehydratase
  • PFL0480w (HMBS, PBGD) porphobilinogen deaminase
  • PF14_0382 (SPP) stromal-processing peptidase, putative
  • PFD1105w (AARP) asparagine-rich protein
  • PFC0110w (CLAG 3.1, RhopH1 3.1, Clag3.1) cytoadherence linked asexual protein 3.2
  • PFC0525c (GSK-3) glycogen synthase kinase 3
  • PF11_0506 (Pf332) antigen 332, DBL-like protein
  • PF13_0252 (NT1, ENT1) nucleoside transporter 1
  • PFB0210c (HT1) hexose transporter
  • PF11_0396 (PP2C) protein phosphatase 2c
  • PFD0100c (surf4.1) surface-associated interspersed gene 4.1, (SURFIN4.1)
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • MAL7P1.176 (EBA-175, EBA175) erythrocyte binding antigen-175
  • PF10_0306 (MORN1) MORN repeat protein, putative
  • PF10_0155 (enolase) enolase
  • PFI0450c (ARP) apoptosis-related protein, putative
  • PFI0050c (RIFIN) rifin
  • MAL13P1.214 (pmt) phosphoethanolamine N-methyltransferase
  • PFL0620c (Gatp) glycerol-3-phosphate acyltransferase
  • PFA0445w (CCp5) LCCL domain-containing protein
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PFL0740c (Cpn10) 10 kd chaperonin
  • PF13_0180 (Cpn20) cochaperonin
  • MAL7P1.150 (IscS) cysteine desulfurase, putative
  • PFL1545c (Cpn60-2) chaperonin, cpn60
  • PF08_0066 (aLipDH) lipoamide dehydrogenase
  • PFL1550w (mLipDH) lipoamide dehydrogenase
  • PFE0150c (IspE) 4-diphosphocytidyl-2c-methyl-D-erythritol kinase (CMK), putative
  • PF10_0218 (CS, CSP, citrate synthase) citrate synthase, mitochondrial precursor, putative
  • PFI1730w (CLAG9) cytoadherence linked asexual protein 9
  • PFI0265c (RhopH3, Rhop-3) high molecular weight rhoptry protein 3
  • PFC0380w (YVH1) dual specificity phosphatase
  • PFB0095c (EMP3) erythrocyte membrane protein 3
  • PFB0100c (KAHRP, HRP1) knob-associated histidine-rich protein
  • PF11_0486 (MAEBL) merozoite adhesive erythrocytic binding protein
  • MAL13P1.60 (EBA140, EBA-140, BAEBL) erythrocyte binding antigen-140
  • PFF1105c (chorismate synthase, CS) chorismate synthase
  • MAL13P1.185 (PK6) protein kinase 6
  • PFA0410w (ARP) conserved Plasmodium protein, unknown function
  • PFI1260c (HDAC1) histone deacetylase
  • PFB0310c (MSP-4, MSP4) merozoite surface protein 4
  • PFF1370w (PK4) protein kinase PK4
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • PFA0125c (EBA-181, JSEBL, EBA181) erythrocyte binding antigen-181
  • PFD0295c (ASP) apical sushi protein
  • PFI1445w (RhopH2) high molecular weight rhoptry protein 2
  • PFL0870w (PTRAMP) thrombospondin-related apical membrane protein
  • PFD0240c ( 41, Pf41) 6-cysteine protein
  • PF10_0343 (S-antigen) S-antigen
  • PF10_0344 (GLURP) glutamate-rich protein
  • PFE0370c (SUB1) subtilisin-like protease 1
  • PFA0110w (RESA) ring-infected erythrocyte surface antigen
  • PFB0335c (SERP H, SERA6, SERP-H) serine repeat antigen 6
  • MAL7P1.208 (RAMA p60, RAMA) rhoptry-associated membrane antigen
  • PFB0300c (MSP-2, Ag513) merozoite surface protein 2
  • PF10_0352 (H103, MSP3.6) merozoite surface protein
  • PFE0340c (Rom-4) rhomboid protease ROM4
  • PFE0120c (MSP-8) merozoite surface protein 8,ring-stage membrane protein 1
  • MAL7P1.119 (RALP1) rhoptry-associated leucine zipper-like protein 1
  • PFL0150w (Orc1, ORC1) origin recognition complex subunit 1
  • PF13_0152 (Sir2) transcriptional regulatory protein sir2a
  • PFF0530w (Tk) transketolase
  • PFL1315w (K1, pfkch1) potassium channel protein
  • PF14_0622 (K2) potassium channel protein
  • PFE0040c (MESA, EMP2) mature parasite-infected erythrocyte surface antigen,erythrocyte membrane protein 2
  • PF10_0368 (DYN2) dynamin-like protein
  • PF13_0085 (UBC13) serine/threonine protein kinase
  • PF11_0224 (exp-1, EXP1, EXP-1) circumsporozoite-related antigen
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • PFI0580c (Falstatin) falstatin
  • PFL0145c (HMGB1) high mobility group protein
  • MAL8P1.72 (HMGB2) high mobility group protein
  • PFE1195w (Kb) karyopherin beta
  • PFL0565w (j4) heat shock protein DNAJ homologue Pfj4
  • PFI0930c (NAPS, NapS) nucleosome assembly protein
  • PFL0185c (NAPL) nucleosome assembly protein
  • PFL2275c (FKBP35) FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
  • PF08_0129 (CnA) serine/threonine protein phosphatase, putative
  • PF13_0080 (TERT) telomerase reverse transcriptase, putative
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PF11_0174 (DPAP1) cathepsin C, homolog,dipeptidyl peptidase 1
  • PF14_0652 (D13) conserved Plasmodium protein, unknown function
  • PFE0690c (Rab1A) Rab GTPase 1a
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PF11_0098 (ERC, ERC1, Pfs40, Pf39) endoplasmic reticulum-resident calcium binding protein
  • MAL13P1.122 (SET2) SET domain protein, putative
  • PF13_0293 (SET6) histone-lysine N-methyltransferase, putative
  • PFL0575w (LSD1) lysine-specific histone demethylase 1, putative
  • PFL1010c conserved Plasmodium protein, unknown function
  • PF08_0012 (KMT1, SET3) SET domain protein, putative
  • PFI0250c (Nup100) conserved Plasmodium membrane protein, unknown function
  • PFL1435c (MyoD) myosin D
  • PFE0285c (SUMO) small ubiquitin-related modifier, putative
  • PFD1165w (FIKK4.1) serine/threonine protein kinase, FIKK family
  • PFI0105c (FIKK9.3) serine/threonine protein kinase, FIKK family
  • PFI0120c (FIKK9.6) serine/threonine protein kinase, FIKK family
  • PFC0160w (AnkDHHC) palmitoyl transferase
  • PFD1150c (RH4) reticulocyte binding protein homologue 4
  • PFD0110w (NBP-1, Rh1) normocyte binding protein 1,reticulocyte binding protein homologue 1
  • PF13_0133 (PM V, PM5, PMV) plasmepsin V
  • PF11_0139 (PRL, EP) protein tyrosine phosphatase
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • PFL2225w (MTIP) myosin A tail domain interacting protein
  • PF14_0016 (SEP14) early transcribed membrane protein 14.1
  • PF11_0040 (SEP11.1) early transcribed membrane protein 11.2
  • PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4
  • PFI1160w (LplA2) lipoate protein ligase a type 2
  • PFB0505c (FabH) beta-ketoacyl-ACP synthase III
  • PFF1130c (SOD2) superoxide dismutase
  • PF14_0495 (RON2) rhoptry neck protein 2
  • PFB0480w (Stx1) syntaxin, Qa-SNARE family
  • PF10_0345 (MSP3.1, MSP3) merozoite surface protein 3
  • PFB0680w (RON6) rhoptry neck protein 6
  • PF11_0168 (RON4, Pf225) rhoptry neck protein 4
  • PFF0775w (PdxK) pyridoxine kinase
  • MAL8P1.3 (25-IMP) Plasmodium exported protein (hyp9), unknown function
  • PFL1005c (HP1, H1) heterochromatin protein 1
  • PF14_0242 (PRMT1) arginine methyltransferase 1
  • PF10_0348 (DBLMSP, MSP3.7, H103) duffy binding-like merozoite surface protein
  • PFI0735c (NDH) type II NADH:quinone oxidoreductase
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PF14_0498 (sDer1-1, Der1-Pl) DER1-like protein
  • PF14_0653-a (hDer1-1) derlin-1
  • PF14_0653-b derlin-1
  • PF13_0182 (sUba1) ubiquitin-activating enzyme
  • PFB0190c (Sel1) conserved Plasmodium protein, unknown function
  • PF14_0462 (Sel2) ubiquitin-protein ligase, putative
  • PF11_0220 (EK) protein kinase
  • PF14_0344 (PTEX150) translocon component PTEX150
  • PF11_0175 (HSP101, ClpB2) heat shock protein 101
  • PFD1110w (GAPM2) glideosome associated protein with multiple membrane spans 2
  • PF14_0065 (GAPM3) glideosome associated protein with multiple membrane spans 3, putative
  • PF14_0112 (PREX) plastid replication-repair enzyme
  • PF14_0294 (map-1) mitogen-activated protein kinase 1
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • PFI0550w (CRMP1) cysteine repeat modular protein 1
  • MAL7P1.92 (CRMP2) cysteine repeat modular protein 2
  • PFC0140c (NSF) N-ethylmaleimide sensitive fusion protein, putative
  • PF13_0328 (PCNA, PCNA1) proliferating cell nuclear antigen
  • PFB0720c (ORC5) origin recognition complex subunit 5
  • PFA0345w-b (CEN1) centrin-1
  • PF14_0443 (CEN2) centrin-2
  • PF10_0271 (CEN3) centrin-3
  • PF11_0066 (CEN4) centrin-4
  • PFI0180w (A-tubulin) alpha tubulin 1
  • PF13_0218 (MDR5) ABC transporter (MDR family), putative
  • MAL7P1.91 (FEST) exported serine/threonine protein kinase
  • MAL13P1.310 (calpain) calpain
  • PF14_0020 (CK) choline kinase
  • PF11_0257 (EK) ethanolamine kinase, putative
  • PF14_0368 (TPx-1) thioredoxin peroxidase 1
  • PFL0725w (pftrx-px2, TPx-2) thioredoxin peroxidase 2
  • PFI1570c (DAP, M18AAP) M18 aspartyl aminopeptidase
  • PFA0330w (AARP2) small ribosomal subunit assembling AARP2 protein
  • PFL1480w (Sec13p) protein transport protein Sec13, putative
  • PFI1755c (REX3, Rex3) ring-exported protein 3
  • PF11_0145 (GloI) glyoxalase I
  • PFD0311w (cGloII) cytosolic glyoxalase II
  • PFL0285w (tGloII) targeted glyoxalase II
  • PF10_0164 (ETRAMP10.3) early transcribed membrane protein 10.3
  • PFE0610c (MAT1) CDK-activating kinase assembly factor
  • PFD0740w (crk-3) cdc2-related protein kinase 3
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • MAL8P1.46 (DLC1) dynein light chain 1
  • PF13_0233 (MyoA, -myo1) myosin A
  • PF11_0061 (H4, h4k5ac, H4K5Ac, H4K8Ac, H4Ac4) histone H4
  • PFF0510w (H3, h3k9m3, h3k9ac, H3K9Me1, H3K9me3, H3K9ac) histone H3
  • MAL8P1.32 (NT2) nucleoside transporter 2
  • PFE0435c (SSB) single-strand binding protein, putative
  • PF13_0258 (TKL3) serine/threonine protein kinase
  • PFC1050w (TSN, Tudor-SN) survival of motor neuron (SMN)-like protein
  • PF11_0192 (MYST) histone acetyltransferase, putative
  • PF08_0071 (SOD1) Fe-superoxide dismutase
  • PF14_0177 (MCM2) minchromosome maintenance (MCM) complex subunit
  • PF13_0291 (MCM6) minchromosome maintenance (MCM) complex subunit
  • PFB0345c (SERA4, SERA3) serine repeat antigen 4
  • PFI0240c (CuP-ATPase) Cu2 -transporting ATPase, putative
  • PFI1735c (REX1) ring-exported protein 1
  • PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative
  • PFE0160c (SR1) Ser/Arg-rich splicing factor, putative
  • PF10_0168-a (GRASP2) golgi re-assembly stacking protein 2
  • PFB0200c (AspAT) aspartate aminotransferase
  • PF14_0534 (SHMTm) serine hydroxymethyltransferase, putative
  • PFL1720w (SHMTc) serine hydroxymethyltransferase
  • MAL13P1.279 (PK5, CDPK5) protein kinase 5
  • PFL2505c (RON3) conserved Plasmodium protein, unknown function
  • PF10_0268 (MCP-1, nPrx) merozoite capping protein 1
  • PF13_0095 (MCM4) minchromosome maintenance (MCM) complex subunit, putative
  • PF14_0408 (SRPK2, CLK-2) serine/threonine protein kinase, putative
  • PF14_0025 (Rpn6) proteosome subunit, putative
  • PFC0920w (H2A.Z) histone H2A variant, putative
  • PF14_0641 (Dxr) 1-deoxy-D-xylulose 5-phosphate reductoisomerase
  • PFF0860c (H2A) histone H2A

Plasmodium yoelii

  • PY04499 (LISP1) hypothetical protein
  • PY06644 (enolase) enolase
  • PY00414 (2-Cys Prx) thioredoxin peroxidase 1
  • PY04285 (1-Cys Prx) 1-cys peroxidoxin
  • PY04421 (HEP17, exp-1) U43539 hepatocyte erythrocyte protein 17 kDa
  • PY05748 (MSP-1, MSP1) merozoite surface protein 1 precursor
  • PY01365 (PY01365) rhoptry protein
  • PY01581 (AMA1) apical membrane antigen-1
  • PY04764 (EBL) duffy receptor, beta form precursor
  • PY02159 (P140, RON4) Drosophila melanogaster CG15040 gene product

Plasmodium berghei

Plasmodium vivax

Also known as all rbc stages, rbc stages.

Toxoplasma gondii

Theileria annulata

  • TA14920 (HSP70, mthsp70) heat shock protein HSP70 homologue, putative
  • TA06510 (-gp34) hypothetical protein
  • TA17315 (PIM) surface protein precursor (TaSP), putative

Theileria parva

Plasmodium gallinaceum

  • DQ068022 (SES) gi|68521875|gb|DQ068022.1| Plasmodium gallinaceum SES mRNA, complete cds

Eimeria tenella

  • AF042329 (Hsp90) gi|2792526|gb|AF042329.1| Eimeria tenella heat shock protein 90 (hsp90) mRNA, complete cds
  • AF353515 (Enolase) gi|13774514|gb|AF353515.1| Eimeria tenella enolase mRNA, complete cds