ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Parasite plasma membrane

Proteins expressed during this time are known in Babesia bovis, Babesia gibsoni, Cryptosporidium parvum, Eimeria tenella, Neospora caninum, Plasmodium berghei, Plasmodium falciparum, Plasmodium gallinaceum, Plasmodium knowlesi, Plasmodium malariae, Plasmodium vivax, Plasmodium yoelii, Theileria annulata, Theileria lestoquardi, Theileria parva, Toxoplasma gondii.

More specific localisations within the parasite plasma membrane umbrella with a localised protein: straight side of d shaped parasite, ookinete surface, nowhere except sporozoite surface, nowhere except parasite plasma membrane, proximal to plasma membrane, plasma membrane surounding oocyst cytoplasm, cyst wall, surrounding parasite, vesicle-like structure just under the parasite membrane, plasma membrane, under parasite plasma membrane, vesicles near parasite surface, parasite plasma membrane, underneath plasma membrane, surface, sporozoite surface, outer membrane of cyst wall

Some proteins may have been specifically not localised here as well.

Babesia bovis

  • BBOV_I003020 (MSA-2c) merozoite surface antigen-2c (MSA-2c)
  • BBOV_I003060 (MSA-1) merozoite surface antigen-1 (MSA-1)
  • BBOV_I003010 (MSA-2a1) merozoite surface antigen-2a1 (MSA-2a1)
  • BBOV_I003000 (MSA-2a2) merozoite surface antigen-2a2 (MSA-2a2)
  • BBOV_I002990 (MSA-2b) merozoite surface antigen-2b (MSA-2b)

Babesia gibsoni

  • DQ386864 (RAP-1a) gi|88770793|gb|DQ386864.1| Babesia gibsoni rhoptry-associated protein mRNA, complete cds
  • FJ608703 (P22) gi|223036619|gb|FJ608703.1| Babesia gibsoni isolate BgP22 merozoite 22-kDa protein mRNA, partial cds
  • AB051834 (P50) gi|14646758|dbj|AB051834.1| Babesia gibsoni P50 mRNA, complete cds

Cryptosporidium parvum

  • cgd6_1080 (gp40/15, gp15, gp-15, GP15, GP40, gp40) conserved hypothetical protein
  • cgd6_780 (MIC1, TSP8) CpTSP8,predicted extracellular protein with 3 TSP1 repeats, an EGF domain and a C-terminal transmembrane domain. adjacent TSP domain containing gene.
  • cgd7_4020 (GP900, gp900) cryptopsoridial mucin, large thr stretch, signal peptide sequence
  • cgd6_5410 (CP2) signal peptide plus thr stretch, charged repeats, likely mucin
  • cgd4_2330 (CP12) hypothetical protein

Eimeria tenella

  • AJ306453 (MIC4) gi|187340650|emb|AJ306453.2| Eimeria tenella mRNA for microneme protein 4 (mic4 gene)
  • AJ245536 (MIC5) gi|5708121|emb|AJ245536.1| Eimeria tenella mRNA for microneme protein 5 (mic-5 gene)
  • Z71755 (MIC2) gi|209414697|emb|Z71755.2| Eimeria tenella mRNA for acidic microneme protein precursor, clone Etmic-2
  • AJ586535 (SAG4) gi|37699771|emb|AJ586535.1| Eimeria tenella mRNA for surface antigen 4 (sag4 gene)
  • AJ586531 (SAG1) gi|38602660|emb|AJ586531.2| Eimeria tenella mRNA for surface antigen 1 (sag1 gene)
  • AJ586543 (SAG13) gi|37699787|emb|AJ586543.1| Eimeria tenella mRNA for surface antigen 13 (sag13 gene)
  • AJ586537 (SAG8) gi|37699775|emb|AJ586537.1| Eimeria tenella mRNA for surface antigen 8 (sag8 gene)

Neospora caninum

Plasmodium berghei

Plasmodium falciparum

  • PF13_0201 (TRAP, SSP2) sporozoite surface protein 2
  • PF14_0541 (VP1, V-type H(+)-translocating pyrophosphatase) V-type H( )-translocating pyrophosphatase, putative
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • PF13_0252 (NT1, ENT1) nucleoside transporter 1
  • PFB0210c (HT1) hexose transporter
  • PFL0795c (mdv-1, peg3, mdv1, Mdv-1, Peg3) male development gene 1
  • PF14_0679 (SulP) inorganic anion exchanger, inorganic anion antiporter
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • PF10_0155 (enolase) enolase
  • PF14_0723 (CCp1) LCCL domain-containing protein
  • PF14_0532 (CCp2) LCCL domain-containing protein
  • PF14_0067 (CCp3) LCCL domain-containing protein
  • PFI0185w (CCp4) LCCL domain-containing protein
  • PFA0445w (CCp5) LCCL domain-containing protein
  • PF14_0491 (FNPA) LCCL-like protein
  • PF10_0303 (Pfs25, P25) 25 kDa ookinete surface antigen precursor
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PF11_0313 (P0) 60S ribosomal protein P0
  • PFB0405w (Pf230, Pfs230) 6-cysteine protein
  • PF11_0486 (MAEBL) merozoite adhesive erythrocytic binding protein
  • PF07_0006 (STARP) sporozoite threonine and asparagine-rich protein
  • PFE0830c (MB2) sporozoite surface antigen MB2
  • PF13_0065 (Vacuolar ATP H+ Synthase subunit a) vacuolar ATP synthase subunit a
  • PFA0410w (ARP) conserved Plasmodium protein, unknown function
  • PFE0545c (TCTP) translationally controlled tumor protein homolog, putative
  • PFB0310c (MSP-4, MSP4) merozoite surface protein 4
  • PFL0870w (PTRAMP) thrombospondin-related apical membrane protein
  • PFI1445w (RhopH2) high molecular weight rhoptry protein 2
  • PF13_0338 (Pf92) cysteine-rich surface protein
  • PFF0615c (Pf12) 6-cysteine protein
  • PFD0240c ( 41, Pf41) 6-cysteine protein
  • PFF0995c (MSP-10) merozoite surface protein 10
  • PF10_0345 (MSP3.1, MSP3) merozoite surface protein 3
  • PFL1385c (ABRA, MSP9, MSP-9) merozoite surface protein 9
  • PF13_0197 (p22, MSP7) merozoite surface protein 7 precursor
  • PF10_0346 (MSP-6 36, MSP3.2, MSP6) merozoite surface protein 6
  • PFB0305c-a (MSP-5) merozoite surface protein 5
  • PFE0340c (Rom-4) rhomboid protease ROM4
  • MAL7P1.176 (EBA-175, EBA175) erythrocyte binding antigen-175
  • PFE0120c (MSP-8) merozoite surface protein 8,ring-stage membrane protein 1
  • PFB0100c (KAHRP, HRP1) knob-associated histidine-rich protein
  • PF11_0465 (DYN1) dynamin-like protein
  • MAL13P1.206 (PiT) sodium-dependent phosphate transporter
  • PF13_0248 (Pfs47) 6-cysteine protein
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PF10_0159 (GBP130) glycophorin binding protein
  • PFB0480w (Stx1) syntaxin, Qa-SNARE family
  • MAL8P1.3 (25-IMP) Plasmodium exported protein (hyp9), unknown function
  • PF07_0072 (CDPK4) calcium dependent protein kinase 4
  • PF10_0348 (DBLMSP, MSP3.7, H103) duffy binding-like merozoite surface protein
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • MAL7P1.92 (CRMP2) cysteine repeat modular protein 2
  • PF13_0247 (s-48/45) 6-cysteine protein
  • PFL1410c (MRP2) ABC transporter, (CT family)
  • PF13_0218 (MDR5) ABC transporter (MDR family), putative
  • PFD0255w (mag-1) ag-1 blood stage membrane protein homologue
  • PFC0210c (CS) circumsporozoite (CS) protein
  • PF14_0201 (Pf113) surface protein, Pf113
  • PFI0240c (CuP-ATPase) Cu2 -transporting ATPase, putative
  • PFL1700c (VP1) V-type K -independent H -translocating inorganic pyrophosphatase

Plasmodium gallinaceum

Plasmodium knowlesi

  • PKH_040760 (SPATR) SPATR protein, putative
  • PKH_041300 (MSP-4, MSP4) merozoite surface protein, putative

Plasmodium malariae

  • J03992 (CS) gi|160220|gb|J03992.1|PFACSPG Plasmodium malariae (clone 255A) circumsporozoite protein (CSP) gene, complete cds

Plasmodium vivax

  • PVX_000995 (Pv41) transmission-blocking target antigen Pfs230, putative
  • PVX_111175 (Pvs25, Pvs28) ookinete surface protein Pvs25
  • PVX_003775 (MSP4) merozoite surface protein 4, putative

Plasmodium yoelii

  • PY06415 (pAg-2) merozoite surface protein precursor
  • PY00522 (Pys25) 28 kDa ookinete surface protein
  • PY03052 (TRAP) sporozoite surface protein 2 precursor
  • PY03168 (CS, CSP, S2) circumsporozoite protein
  • PY06644 (enolase) enolase
  • PY05748 (MSP-1, MSP1) merozoite surface protein 1 precursor

Theileria annulata

  • TA20205 (SE) schizont protein e
  • TA19865 (D) surface protein d precursor
  • TA06510 (-gp34) hypothetical protein
  • TA17315 (PIM) surface protein precursor (TaSP), putative

Theileria lestoquardi

  • DQ004498 (clone-5) gi|63079800|gb|DQ004498.1| Theileria lestoquardi unknown protein long splice variant mRNA, complete cds, alternatively spliced

Theileria parva

  • TP01_0939 (-gp34) hypothetical protein
  • TP04_0051 (PIM) polymorphic immunodominant molecule

Toxoplasma gondii