ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)


Proteins expressed during this time are known in Babesia bovis, Babesia equi, Babesia gibsoni, Cryptosporidium parvum, Eimeria ascervulina, Eimeria maxima, Eimeria tenella, Neospora caninum, Plasmodium berghei, Plasmodium falciparum, Plasmodium gallinaceum, Plasmodium malariae, Plasmodium yoelii, Sarcocystis muris, Toxoplasma gondii.

More specific localisations within the other umbrella with a localised protein: between endoplasmic reticulum and golgi, osmiophilic body, intravacuolar tubular network, cone shaped body of basal complex, cell surface, posterior, cytoplasmic structure, subcapsular areas, intravacuolar network, evacuole, cytostome, periphery of amylopectin-like granules, vesicles, microtubule, prerhoptry, vacuole, residual body, multi-vesicular endosome, cytoplasmic vesicle, food vacuole region, flagellar basal bodies, anterior adjacent to mitochondrion, gliding trail, centrocone, adjacent to mitochondrion, electron-dense heterochromatic region at the nuclear periphery, early endosome, feeder organelle, between pellicle and parasitophorous vacuole membrane, membrane structure, cell poles, endosome-related compartment, vesicle, released into extracellular mileiu, beyond erythrocyte membrane, dense band, merozoite associated material, spindle pole, intracellular vacuole membrane, inner surface of peripheral vacuoles, individual merozoites inside merozomes, area near nucleus, residual body membrane, exflagellation centre, periphery, developing cyst wall, peroxisome, two unknown vesicular bodies, anterior to nucleus, acidocalcisome, crystalloid body, zygote remnant, ookinete protrusion, reticular staining outside apicoplast, posterior vesicle, acrosome, p-body, surrounding, basal of nucleus, centriole, zygote side, posterior structure, multi-lamellar vesicle, wall forming body, wall forming body type ii, spread around parasite, crystalloid, around cytomeres, intracellular vacuole, endosomal membrane, centrosome, endosomal vacuole, vesicle budding off zoite posterior, area around nucleus, cyst matrix, near apicoplast membranes, cytoskeleton, flagellate basal body, internal structures, anterior adjacent to mitochondria, oocyst capsule, posterior extremity of cup-shaped inner membrane cytoskeleton scaffolds, transformation bulb, transport vesicle, invasion furrow, lysosome, oocyst wall, posterior to nucleus, posterior cytoplasm, non-invasion-related localisation, subpellicular microtubule, basal, adjacent to the inner membrane complex, extracellular, tubulovesicular membrane, ookinete apical surface, internal membrane networks, basal complex

Some proteins may have been specifically not localised here as well.

Babesia bovis

Babesia equi

  • AB043618 (EMA-1) gi|8096552|dbj|AB043618.1| Babesia equi EMA-1 gene for merozoite antigen 1, complete cds
  • AB013725 (EMA-2) gi|3142236|dbj|AB013725.1| Babesia equi gene for merozoite antigen 2, complete cds

Babesia gibsoni

  • AB051834 (P50) gi|14646758|dbj|AB051834.1| Babesia gibsoni P50 mRNA, complete cds
  • AB083515 (Hsp70) gi|23867855|dbj|AB083515.1| Babesia gibsoni hsp70 mRNA for heat shock protein 70, complete cds, strain: Korea4

Cryptosporidium parvum

  • cgd6_5410 (CP2) signal peptide plus thr stretch, charged repeats, likely mucin
  • cgd1_700 (ABC, ABC1) ATP-binding cassette protein
  • cgd6_2090 (COWP-190, COWP, COWP1) CpCOWP1, oocyst wall protein with type I and type II cysteine-rich repeats
  • cgd6_200 (COWP8) oocyst wall protein 8
  • cgd4_690 (PNO) pyruvate:ferredoxin oxidoreductase/NADPH-cytochrome P450 reductase PNO
  • cgd6_1080 (gp40/15, gp15, gp-15, GP15, GP40, gp40) conserved hypothetical protein

Eimeria ascervulina

Eimeria maxima

Eimeria tenella

Neospora caninum

Plasmodium berghei

Plasmodium falciparum

  • PFB0640c (Sec31, Sec31p) sec31p
  • PF13_0280 (ERD2) ER lumen protein retaining receptor
  • PF14_0077 (PM II, PM2, PMII, Plasmepsin II) plasmepsin II
  • PF11_0165 (Falcipain-2, FP2) cysteine proteinase falcipain 2a
  • PFC0890w (Sec22) SNARE protein
  • PFD0310w (Pfs16) sexual stage-specific protein precursor
  • PFL0795c (mdv-1, peg3, mdv1, Mdv-1, Peg3) male development gene 1
  • PFD0100c (surf4.1) surface-associated interspersed gene 4.1, (SURFIN4.1)
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • PF10_0306 (MORN1) MORN repeat protein, putative
  • PF14_0723 (CCp1) LCCL domain-containing protein
  • PFA0445w (CCp5) LCCL domain-containing protein
  • PF14_0491 (FNPA) LCCL-like protein
  • PF10_0303 (Pfs25, P25) 25 kDa ookinete surface antigen precursor
  • PF13_0152 (Sir2) transcriptional regulatory protein sir2a
  • MAL13P1.326 (FC, HemH) ferrochelatase
  • PFD0810w (Sar1p, Sar1) small GTP-binding protein sar1
  • PF13_0065 (Vacuolar ATP H+ Synthase subunit a) vacuolar ATP synthase subunit a
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PF10_0356 (LSA-1) liver stage antigen 1
  • PFL2405c (g377) osmiophilic body protein
  • PF10_0368 (DYN2) dynamin-like protein
  • PFL0185c (NAPL) nucleosome assembly protein
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PFL1090w (GAP45) glideosome-associated protein 45
  • PFL1435c (MyoD) myosin D
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • MAL7P1.27 (CRT) chloroquine resistance transporter
  • PFL1660c conserved Plasmodium protein, unknown function
  • PFC0435w parasite-infected erythrocyte surface protein
  • PF14_0067 (CCp3) LCCL domain-containing protein
  • PFB0190c (Sel1) conserved Plasmodium protein, unknown function
  • PF14_0462 (Sel2) ubiquitin-protein ligase, putative
  • PF11_0220 (EK) protein kinase
  • PF11_0139 (PRL, EP) protein tyrosine phosphatase
  • PFE1290w (Nek2) NIMA related kinase 2
  • PF14_0344 (PTEX150) translocon component PTEX150
  • PF11_0175 (HSP101, ClpB2) heat shock protein 101
  • PF14_0443 (CEN2) centrin-2
  • PF10_0271 (CEN3) centrin-3
  • PFI0180w (A-tubulin) alpha tubulin 1
  • PFL2510w (CHT1) chitinase
  • PFB0500c (Rab5a, Rab5) Rab GTPase 5a
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PFE0910w conserved Plasmodium protein, unknown function
  • PFI1565w profilin, putative
  • PF11_0190 haloacid dehalogenase-like hydrolase, putative
  • PF14_0092 conserved Plasmodium membrane protein, unknown function
  • PF14_0222 ankyrin, putative
  • PF14_0369 copper transporter putative
  • MAL13P1.215 conserved Plasmodium protein, unknown function
  • MAL8P1.79 conserved Plasmodium protein, unknown function
  • PFL2100w ubiquitin conjugating enzyme E2, putative
  • PFC0945w protein kinase, putative
  • PFI0880c (GAP50, SAP) glideosome-associated protein 50,secreted acid phosphatase
  • PFE0765w (PI3K) phosphatidylinositol 3-kinase
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • PFL1555w cytochrome b5, putative
  • PF13_0258 (TKL3) serine/threonine protein kinase
  • PF14_0534 (SHMTm) serine hydroxymethyltransferase, putative
  • PFL1720w (SHMTc) serine hydroxymethyltransferase

Plasmodium gallinaceum

Plasmodium malariae

  • J03992 (CS) gi|160220|gb|J03992.1|PFACSPG Plasmodium malariae (clone 255A) circumsporozoite protein (CSP) gene, complete cds

Plasmodium yoelii

  • PY03168 (CS, CSP, S2) circumsporozoite protein
  • PY03052 (TRAP) sporozoite surface protein 2 precursor
  • PY00204 (S3, UIS4) hypothetical protein
  • PY03011 (S7) early transcribed membrane protein family

Sarcocystis muris

  • AAA29805 (31-kDa) gi|160822|gb|AAA29805.1| 31-kDa major surface antigen [Sarcocystis muris]

Toxoplasma gondii