ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Cytoplasm

Proteins expressed during this time are known in Babesia bigemina, Babesia bovis, Babesia gibsoni, Babesia microti, Cryptosporidium parvum, Eimeria tenella, Neospora caninum, Plasmodium berghei, Plasmodium chabaudi, Plasmodium falciparum, Plasmodium vivax, Plasmodium yoelii, Theileria annulata, Toxoplasma gondii.

More specific localisations within the cytoplasm umbrella with a localised protein: cytoplasm, intracellular, merozoite cytosol, intracellular inclusion, cytoplasmic accumulation, cytoplasm proximal to amylopectin-like granules, cytoplasmic foci, cytosol, peripheral, periphery of parasite

Some proteins may have been specifically not localised here as well.

Babesia bigemina

  • AF142406 (p200) gi|7549209|gb|AF142406.1| Babesia bigemina 200 kDa antigen p200 mRNA, partial cds

Babesia bovis

Babesia gibsoni

  • DQ386864 (RAP-1a) gi|88770793|gb|DQ386864.1| Babesia gibsoni rhoptry-associated protein mRNA, complete cds
  • AB480715 (RAP-1b) gi|255708245|dbj|AB480715.1| Babesia gibsoni BgRAP-1b mRNA for rhoptry-associated protein-1b, complete cds
  • AB480716 (RAP-1c) gi|255708247|dbj|AB480716.1| Babesia gibsoni BgRAP-1c mRNA for rhoptry-associated protein-1c, complete cds
  • AB490782 (LAP) gi|253735627|dbj|AB490782.1| Babesia gibsoni BgLAP mRNA for leucine aminopeptidase, complete cds

Babesia microti

Cryptosporidium parvum

  • cgd3_2180 (FAS1 Type I) type I fatty acid synthase
  • cgd8_4740 (SFP-PPT, PPTase) phosphopantetheinyl transferase
  • cgd4_2900 (PKS1) polyketide synthase
  • cgd1_700 (ABC, ABC1) ATP-binding cassette protein
  • cgd6_5410 (CP2) signal peptide plus thr stretch, charged repeats, likely mucin
  • cgd4_690 (PNO) pyruvate:ferredoxin oxidoreductase/NADPH-cytochrome P450 reductase PNO
  • cgd6_2330 (p30) hypothetical protein with signal peptide

Eimeria tenella

  • AJ306453 (MIC4) gi|187340650|emb|AJ306453.2| Eimeria tenella mRNA for microneme protein 4 (mic4 gene)
  • AJ245536 (MIC5) gi|5708121|emb|AJ245536.1| Eimeria tenella mRNA for microneme protein 5 (mic-5 gene)
  • AF042329 (Hsp90) gi|2792526|gb|AF042329.1| Eimeria tenella heat shock protein 90 (hsp90) mRNA, complete cds
  • GQ463153 (GFAT) gi|258562383|gb|GQ463153.1| Eimeria tenella glucosamine: fructose-6-phosphate aminotransferase mRNA, partial cds

Neospora caninum

Plasmodium berghei

Plasmodium chabaudi

Plasmodium falciparum

  • PF13_0201 (TRAP, SSP2) sporozoite surface protein 2
  • PFI1755c (REX3, Rex3) ring-exported protein 3
  • PFI1760w (REX4) ring-exported protein 4
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • PF07_0059 (PNPase) 4-nitrophenylphosphatase
  • PFL1465c (HslV) heat shock protein hslv
  • PFI1195c (TPK) thiamine pyrophosphokinase
  • PF14_0541 (VP1, V-type H(+)-translocating pyrophosphatase) V-type H( )-translocating pyrophosphatase, putative
  • PFC0110w (CLAG 3.1, RhopH1 3.1, Clag3.1) cytoadherence linked asexual protein 3.2
  • PF11_0301 (SPDS) spermidine synthase
  • PF11_0396 (PP2C) protein phosphatase 2c
  • PF11_0224 (exp-1, EXP1, EXP-1) circumsporozoite-related antigen
  • PF14_0439 (LAP) M17 leucyl aminopeptidase
  • PF14_0517 (APP) aminopeptidase P
  • PFI1570c (DAP, M18AAP) M18 aspartyl aminopeptidase
  • PF10_0155 (enolase) enolase
  • PFI0450c (ARP) apoptosis-related protein, putative
  • PF14_0020 (CK) choline kinase
  • PF14_0723 (CCp1) LCCL domain-containing protein
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PF14_0053 (R2) ribonucleotide reductase small subunit
  • PF10_0154 (R4) ribonucleotide reductase small subunit, putative
  • PFC0380w (YVH1) dual specificity phosphatase
  • PFB0095c (EMP3) erythrocyte membrane protein 3
  • PFB0400w 6-cysteine protein
  • PFE0830c (MB2) sporozoite surface antigen MB2
  • PFF1105c (chorismate synthase, CS) chorismate synthase
  • MAL13P1.185 (PK6) protein kinase 6
  • PFE0545c (TCTP) translationally controlled tumor protein homolog, putative
  • PF11_0225 (GCN20) ABC transporter GCN20
  • PF10_0153 (Cpn60, Hsp60, hsp60) heat shock protein 60
  • PFL1385c (ABRA, MSP9, MSP-9) merozoite surface protein 9
  • PF13_0197 (p22, MSP7) merozoite surface protein 7 precursor
  • PF13_0348 (Rhop148) rhoptry protein
  • PFL0150w (Orc1, ORC1) origin recognition complex subunit 1
  • PF13_0152 (Sir2) transcriptional regulatory protein sir2a
  • PFF0530w (Tk) transketolase
  • PF11_0338 (AQP) aquaglyceroporin
  • PF14_0622 (K2) potassium channel protein
  • PF13_0085 (UBC13) serine/threonine protein kinase
  • PFI0580c (Falstatin) falstatin
  • MAL8P1.72 (HMGB2) high mobility group protein
  • PFE1195w (Kb) karyopherin beta
  • PFL0565w (j4) heat shock protein DNAJ homologue Pfj4
  • PF08_0054 (hsp, Hsp70-1) heat shock protein 70
  • PFI0930c (NAPS, NapS) nucleosome assembly protein
  • PFL2275c (FKBP35) FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
  • PF08_0129 (CnA) serine/threonine protein phosphatase, putative
  • PF14_0548 (Vps4) ATPase Vps4, putative
  • PF14_0652 (D13) conserved Plasmodium protein, unknown function
  • PF10_0159 (GBP130) glycophorin binding protein
  • PFA0110w (RESA) ring-infected erythrocyte surface antigen
  • PFL1435c (MyoD) myosin D
  • PFE0285c (SUMO) small ubiquitin-related modifier, putative
  • PFI0100c (FIKK9.2) serine/threonine protein kinase, FIKK family
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • PF13_0090 ADP-ribosylation factor, putative
  • PFC0435w parasite-infected erythrocyte surface protein
  • PFD0495c (EVP1) conserved Plasmodium protein, unknown function
  • PFL0590c (ATPase4) non-SERCA-type Ca2 -transporting P-ATPase
  • PFB0680w (RON6) rhoptry neck protein 6
  • PFF0895w (MDH) malate dehydrogenase
  • PFF0775w (PdxK) pyridoxine kinase
  • PF14_0242 (PRMT1) arginine methyltransferase 1
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • PFI0735c (NDH) type II NADH:quinone oxidoreductase
  • PFL0925w (Formin2) formin 2, putative
  • PF13_0011 (g27) gamete antigen 27/25
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • PFD0255w (mag-1) ag-1 blood stage membrane protein homologue
  • MAL13P1.310 (calpain) calpain
  • PF11_0257 (EK) ethanolamine kinase, putative
  • PF14_0368 (TPx-1) thioredoxin peroxidase 1
  • PF08_0131 (1-Cys-Prx) 1-cys peroxiredoxin
  • PF14_0545 (Trx-1) thioredoxin, putative
  • PF14_0346 (PKG) cGMP-dependent protein kinase
  • PF11_0436 (CPO) coproporphyrinogen III oxidase
  • PF11_0461 (Rab6) Rab GTPase 6
  • PF11_0145 (GloI) glyoxalase I
  • PFD0311w (cGloII) cytosolic glyoxalase II
  • PF13_0229 (IRPa) aconitase
  • PFD0825c (Puf2) RNA binding protein Puf2
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • MAL8P1.46 (DLC1) dynein light chain 1
  • PF13_0233 (MyoA, -myo1) myosin A
  • PFI0250c (Nup100) conserved Plasmodium membrane protein, unknown function
  • PF13_0258 (TKL3) serine/threonine protein kinase
  • MAL13P1.56 (A-M1) M1-family alanyl aminopeptidase
  • MAL13P1.61 Plasmodium exported protein (hyp8), unknown function
  • PFF0860c (H2A) histone H2A
  • PF11_0192 (MYST) histone acetyltransferase, putative
  • PFB0445c (U52) DEAD box helicase
  • PF08_0036 (Sec23) Pfsec23
  • PF08_0071 (SOD1) Fe-superoxide dismutase
  • PFI0265c (RhopH3, Rhop-3) high molecular weight rhoptry protein 3
  • PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative
  • PFE0160c (SR1) Ser/Arg-rich splicing factor, putative
  • PFI0515w (Ykt6.1) SNARE protein, putative
  • PFB0200c (AspAT) aspartate aminotransferase
  • PFL1720w (SHMTc) serine hydroxymethyltransferase
  • MAL13P1.279 (PK5, CDPK5) protein kinase 5
  • PFC0635c (eIF4E) translation initiation factor 4E
  • PF13_0095 (MCM4) minchromosome maintenance (MCM) complex subunit, putative
  • PF14_0408 (SRPK2, CLK-2) serine/threonine protein kinase, putative
  • MAL13P1.274 (PP5) serine/threonine protein phosphatase
  • PF14_0025 (Rpn6) proteosome subunit, putative
  • PF10_0026 (PArt) tryptophan-rich antigen 3

Plasmodium vivax

Plasmodium yoelii

  • PY03625 (pypAg-3) secreted blood-stage antigen pAg-3
  • PY00414 (2-Cys Prx) thioredoxin peroxidase 1
  • PY04285 (1-Cys Prx) 1-cys peroxidoxin
  • PY00522 (Pys25) 28 kDa ookinete surface protein

Theileria annulata

  • TA14920 (HSP70, mthsp70) heat shock protein HSP70 homologue, putative
  • TA20205 (SE) schizont protein e
  • TA19865 (D) surface protein d precursor
  • TA10630 (CKIIalpha) casein kinase II, alpha subunit, putative

Toxoplasma gondii