ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

TGME49_100100 (RON2)

rhoptry neck protein 2, a gene from Toxoplasma gondii

Compiled localisation
rhoptry neck during tachyzoite
moving junction during tachyzoite invasion
host cell plasma membrane during tachyzoite

Who localised this protein by microscopy?

Besteiro, S., Michelin, A., Poncet, J., Dubremetz, J. F., Lebrun, M.
Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion. (2009 Feb, PLoS Pathog) PubMed / full text
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moving junction during tachyzoite invasion, host cell plasma membrane and rhoptry neck during tachyzoite

Bradley, P. J., Ward, C., Cheng, S. J., Alexander, D. L., Coller, S., Coombs, G. H., Dunn, J. D., Ferguson, D. J., Sanderson, S. J., Wastling, J. M., Boothroyd, J. C.
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. (2005 Oct 7, J Biol Chem) PubMed / full text
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rhoptry neck during tachyzoite

Orthology

OrthoMCL

Part of OrthoMCL group OG4_27374

Localised Genes in this Group
Other Apicomplexan Genes in this Group
Non-Apicomplexan Genes in this OrthoMCL Group with Gene Ontology 'Inferred from Direct Assay (IDA)' Cellular Component Terms
    There are no non-apicomplexan genes that have manually annotated evidence codes.

Amino Acid Sequence

>TGME49_100100 rhoptry neck protein 2
MTKRAGLPLGRAFLVLILLSAADSLFFSSFPRSALQLFSSVLFTDAAEPDSDATPGLRPQPSPRTFRPTGYQRIEVKTVD
EELPEDLKVYTASTRGSSSRTFEVRNAGGRQEGFTLSVLTAGGPLPHGSWSWSGTPPEVQTTGGSQISFGWVPDTETPSL
PERNLLQLKRMLRDEGLIEAVQLRAAEKGCPVAVLHNLRQLPVNFREVLHEEYESRSNPAKMYEVANSYVQQRGSDAARW
SVSQSVELSLLEMHATSTTDPRGSSAVPSFLETGPQVRVAMTDAVPSGIRVYATPPAPRPVPVQSNQTEKERSPTSKRLV
GMQLGLYLICKLAALFGHPTLFLNPYYTEQQLLEAVAQALGIAPPHRGDFENEGNEAQATANQHNGSADQLLAAIEIFRL
GPNPYTIGHVLTLMIAYLDYESFFGASPSKPFHSWVSLAASAGNNTGFAMLDEMCDNHRGPKRRGQKHWYQTGGARKHKN
RDMLPLHRQLCDALELVLNGVQQIQIDLMDELGKYKTGVEPLVDPATNSARIHTRTCRGLSPVCDYEATILAPVRALEPH
EQQDSLRTKKAFNLVTGYGSGHVGQITGSIAEPFSHSWRTRWGKVVADPTAYGEIFERTLWFDDRELMAKSSGALFRQYD
RIAKDSMSFGVFMNVENGLLKKDMRSKLEAYISQRKSFVEKRQQSRFAKLRKKIPENDPYALRAAIFLALNYPAALHDRQ
HTRVSRNKKTMRILNSKWTPAVLKKLMRKVNHKHMAREAKALLLRSLDPTVLSSIVTAFDFITHTQANLEVNQNAFMYHE
VRAREVSRQSAAEKGSHRLHERGLVRETDDMIKRWAEHGIPGDIKRRLARGEKLPEGMSFGGIPIPNLTNWDAQLNSKWL
EAYNAYLRHPYGRAALNARDPVALLVKDSRDRLQAEAEGTIFLGRIAKRVHQSKNLLRRAGRALKTFFLSLLRENERSEY
AVWFGVKVDMRQVIQTCRQINSVAEVVKNDRLYDFITDGWMELVKDVVAGYTKASVRVPGFDTISAANEQLRKEGVAAAT
ARNQGFLSIHYDYANLPEEERKKEFQRSMCMEQCEALWKLVMAFVMPNLQNPKKLKGYEKDFSGAKEIEKLNSPHHVNAF
RFSLSVQIDFFDNMLDKTSKKNLKAMKFGASTWFTYAMKLAGQVNSEMGNPNLGTALYMQAAYYGNYIRKWMEQRRKSRK
QAIIGVLTLGMMGLYALLNVADIVQHMEDIGGAPPVSCVTNEILGVTCAPQAIAKATTSAARVATQDFLKVGLFAGMAPY
LMLPMAVVSVWNILKSEIKVLLQFEMALKHTFTRLKRWLAAPFKNWWAKRGRLKDALFRRASQTYRKTEQETKQPPRPRN
LHNPSSWGDTELDSLGVPPEPFVQDFEIKYTTPVFPMSAPLIKA

Gene-Specific Links for TGME49_100100

General Sub-Cellular Localisation Links

  • TargetP, prediction of signal peptides, as well as chloroplast and mitochondrial transit peptides
  • OrthoMCL, automatic clustering of orthologous groups of proteins