ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

TGME49_089690 (GAPDH I)

glyceraldehyde-3-phosphate dehydrogenase, a gene from Toxoplasma gondii

Compiled localisation
cytosol during intracellular tachyzoite
inner membrane complex during extracellular tachyzoite

Who localised this protein by microscopy?

Pomel, S., Luk, F. C., Beckers, C. J.
Host cell egress and invasion induce marked relocations of glycolytic enzymes in Toxoplasma gondii tachyzoites. (2008 Oct, PLoS Pathog) PubMed / full text
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cytosol during intracellular tachyzoite, inner membrane complex during extracellular tachyzoite

Fleige, T., Fischer, K., Ferguson, D. J., Gross, U., Bohne, W.
Carbohydrate metabolism in the Toxoplasma gondii apicoplast: localization of three glycolytic isoenzymes, the single pyruvate dehydrogenase complex, and a plastid phosphate translocator. (2007 Jun, Eukaryot Cell) PubMed / full text
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cytosol during intracellular tachyzoite

Orthology

OrthoMCL

Part of OrthoMCL group OG4_10093

Localised Genes in this Group
Other Apicomplexan Genes in this Group
  • PBANKA_132640 glyceraldehyde-3-phosphate dehydrogenase, putative
  • PY03280 glyceraldehyde-3-phosphate dehydrogenase
  • PCHAS_132970 glyceraldehyde-3-phosphate dehydrogenase, putative
  • PKH_124290 glyceraldehyde-3-phosphate dehydrogenase, putative
  • NCLIV_037190 glyceraldehyde-3-phosphate dehydrogenase, putative
  • NCLIV_041940 Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12), related
  • cgd6_3790 glyceraldehyde 3-phosphate dehydrogenase
  • Chro.60434 glyceraldehyde-3-phosphate dehydrogenase
  • CMU_017050 glyceraldehyde-3-phosphate dehydrogenase, type I family protein
  • TP02_0858 glyceraldehyde-3-phosphate dehydrogenase, putative
  • TA08145 glyceraldehyde-3-phosphate dehydrogenase, putative
  • TA15530 glyceraldehyde 3-phosphate dehydrogenase, putative
  • BBOV_II002540 glyceraldehyde-3-phosphate dehydrogenase protein
Non-Apicomplexan Genes in this OrthoMCL Group with Gene Ontology 'Inferred from Direct Assay (IDA)' Cellular Component Terms

Amino Acid Sequence

>TGME49_089690 glyceraldehyde-3-phosphate dehydrogenase
MVCKLGINGFGRIGRLVFRAAMERGDVEVLAINDPFMSLDYMVYLLRYDSVHGHYPGEVSHKDGKLIVGGKAVTVFNEKE
PTAIPWGQAGVHYICESTGIFLTKEKAQAHLTNGAKKVIMSAPPKDDTPMFVMGVNNDQYKSSDVIVSNASCTTNCLAPL
AKIVHDKFGIVEGLMTTVHAMTANQLTVDGPSKGGKDWRAGRSAGVNIIPASTGAAKAVGKIIPSLNGKLTGMAFRVPVP
DVSVVDLTCKLAKPAKYEDIVAAVKEAATSGPMKGIISYTDEEVVSSDFVHCKFSSVFDINAGIMLNDTFVKLVSWYDNE
WGYSNRLVELAHYMSVQDGA

Gene-Specific Links for TGME49_089690

General Sub-Cellular Localisation Links

  • TargetP, prediction of signal peptides, as well as chloroplast and mitochondrial transit peptides
  • OrthoMCL, automatic clustering of orthologous groups of proteins