ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

TGME49_032080 ()

hypothetical protein, conserved, a gene from Toxoplasma gondii

Compiled localisation

Who localised this protein by microscopy?

No manually curated localisations are recorded in ApiLoc, sorry.

Orthology

OrthoMCL

Part of OrthoMCL group OG4_20482

Localised Genes in this Group
    No apicomplexan genes in this OrthoMCL group have been localised.
Other Apicomplexan Genes in this Group
Non-Apicomplexan Genes in this OrthoMCL Group with Gene Ontology 'Inferred from Direct Assay (IDA)' Cellular Component Terms
    There are no non-apicomplexan genes that have manually annotated evidence codes.

Amino Acid Sequence

>TGME49_032080 hypothetical protein, conserved
MLTNILDQLIKTYGHEFLGDWDPINNFRIDSLAEPEVHLTNIPFPQQLFDLAEIPFAVDYSNIAKVRAKFSWQTFFGSPS
SNPFTIEAEDLEIRLRLLYPSEWDAEHWLAKVLKAKRKRIDLWQKFASLFSTSVPDKKSLTQTIEPRIVNALKIHVKNIH
VHLVDDNIHQTPFGFEFKIDEFLIDSPHRGDPRLSEVESTGSENCLLMGLWMRFVGFHLWFREFPRPQLRWRSGPSAFVK
KAQDLRRRLRKNRGDTEARRELNLLLNREAEEAGEADGSQVSSGEQETGAAGSGGEGSGGEAFAQSLSSKKSGLQGSSQS
LDFADCKTDRRDEEEREAPQTDGASGTSAPDSDGRPGGEWRTAFRKSNTTLRRRAYNVAFSTDGESEGCRAWELETTPHG
RVLSRFDTSVGRDGCRESSPRDRGKQGASQLPNPGQGLETDSEKDDAETGGELRSERRLAVKKPSVEALTAQLSREIMDT
LPIRDEGVARALATKAIKKGFLSPTVSLRSTTSEQPVGTAGSGPVATDSGPQSASGGVSSLSGELLDRAQLGERYATRAR
PRRRRQSSLSTPRDEDADCLQGMRAGKAFKVVPSQVRDVLPKNSHAFRVTPETGMEMHILFKKWELRALGSSLPVQQESW
KSVELSFIAHDPSKHPDLGNPIRPPLCAPPSSRLPFFNLHASLESGAQTGSEPEPRALSAPLQEARGAANKVGAAKKAVA
AREASAPIGEKETGGATFPGDRTQPPSPPLMNGQQQHAPLRLSVTSAVVDAFFNFVKLLDMWFLFMKGATRPLKRVASEK
ECKTYVDFWKKKLVGQTKPEDNFEKFVAQFEYSSPLFLVVRLRQIAEDSLSWKDGVSAALLRKQVFRAVTLGTPQNPFSC
AGCRPYVCREEVTTPVADSEFAQEDDAGGARGDDFAEGHALEAEGKEGGFGGKRWFFSDSELQVLVPSLWLEMLPAIKGG
MHIDFPFGLARSRRRRFRDRNSCVAAGGDSDEDALVTGHRRRNADWMRGAGARRLSRKRRSCLKGREEESSLSRRDANGD
RSDVEGSPSRLRKGEASRGVLKSVGLPVESETALGVTAPPDTLRSFASFESGSTPTTSPCSPSNPRRRSIPVALDREGES
RRHSRRRREDSFSWGRGSTLRGNRAGRRSSSNVRGDRTQTLEDIVARGAVFDPLPSTTLCFVFSCDFRFHQKKKSDLVRS
NDIYIDLVHVQKGMMGLQLKRFDRLCYVRTPRAESIQTPLPRYLVTPTPLPYGGWTTVVYMPRFPPSRKGWGVDLARMPR
RPFGGASASPREVPKSSEGEGEYQLIGHHVIQGALNPPFSASVAVSDPLQGSTPRNSPVSREGATVPNAEGRSGETGGGV
GSPVVPFEASVPVRRRSVVSTLTAYMNQIGSRRRSSGANASDHLPDAHQRTGDISARPQGSGTEGPEPRSSNTEEWNEEN
EDVVVGPIGSDRRKSIRIYLADKMLWDEEQERTRSKKKIVVTLPEITVVASELLSLADILPTTFVTLDLFLREDPLMPQS
TLDAIACAVNYCPRCDSTISIQMSEATFVYRHSLLDYGRLNTFLQFERRLQDASAKRRSMGTPTRPEKPSKKSMVERQPS
SGLPRGVTGGRAGPIRRFRTTDFHGVNDDPVISVSRRKLRTIVRDHSFVTTRQLVFGEDRKAHGGVGGQGVMFSTHGPGR
PLDGLFPYYYPGGDANTGLSGRYRYSPVWGEGGEAVHFVGNFEGPPGLPFYDAGGMDLPGLGHPRAWPEVLEFAGPAGDL
LAQGGSGTSGLVNGVPSAGDNEGDESGSAGDRETSETRKCLPQDDEDEGDMWEDTSALYSSDATGLFGPSSSSEEDEEGV
DEEMILEAEREPVESSGFESITEGVQIVVERAKVLIREEKPVGERTIEVDVGVLTAGALLSPCFQADASQSVSQLCKIEK
TRIRLRPNRVNVSVRGVHTGVCTPLWSLGATWKYFLPHTYPFTTAMQDPTASLKKLKQMGQLRNIDAYARMTIAKLEEEQ
YQLMLKEQEWRDSAPRKHEEETKNSRDEKDGGVETEDAGGSLSMADRQKATTAGSATRRHKGDAEVSTCSSRVPGAAGPP
NDQRTQSATGSGDSTKKKIGAKERQADGTLLQRSRPPPLDPPESGVFAEALEPRFSWLFRPGDEHEEGADRRDTKDRGGS
NDDEPEDGARPVGVCFCTGSTGAAKAGEETFEEEAPKEDAKTTAKHASSISGGALSTTARADERDALSRGKPRDVEVLSG
AASGREIDQRQNANGAEILSAQALKSGRGISSDSAALLSSEKQLRMLAAARVATLLATDKAAAANVAKRVVISCEVLNVG
LYTGTQVLAVALSTNEIRVRLDLQGELKAVKAKVGELFMQHVNPVAPPASATGCETQQPLGPSVGSTTNPSHGQQGGEVG
DVAGRRGVRRAGRGGSLGNEPLDSRRDPASLYLTGGALLTGESGSAALGYSSVILCRNVAHLGVGSSETRHTIGLAQHRL
LEEEGHPNLTGDGGDGSSGRGYLSVHAAGRRQVGQGGGARGTRAGHSTGPAELSSIWTGSSGHEGQGRGCKPTGKGSGGL
LRGSSRLRMLPSDGTGEMRDRGLRRPTEAGGSEARTQSAPAARRLGEKGISGGGREKKEQLDAHLTHDFVDNDAEDGEDP
DVGDEESSRQPMALRGGSSGVTDWSLGGSGGPAVSGLPASQVAGVEHGRRENVDDLLEVGPRGAASRSDSRASSGFEARG
LTDDEATLVGVEGGLGSPRSRATTLVSRLDQIARRKAKRESSATGVETNGGDEGENVEAGEGRPDNSPGGFRRSLLRGRT
RRLHASAKTLLTRDDRTTSWRRVTEKAKQLAESSAPAMKTSNTMVKSGRLSSRRARSEDRSLQRKIEYARRGACTVEGKT
GNLDEWRELIEDAEDCFDEDNDEKEFWPDGDRHDEAGTMRLCGSGDPDTQVETFVFGNDVSSRVSGVGNQDGRRGRSADP
AASSPPQIVLFCSVNPEKDTVEANGKLRSVHLFPTVAFTCCVTDIALQSVKFFKEETQRSSLLVASVTDDPLSALVARRH
GMSFLPFGRTQDTDPGMKTRQVHAPGISRSASYRALRDDPGPEPFPYPMQKPPVSVPPPRGRLLDPLLSSGEYDVKAGLS
ANGPCRERNWSQSTAASVSTRRAEDTGSQRKLTASAEDSLGVEARTSGGTQAGTEDDGELKKKGTSRQISVNFVLDDISV
NLLTADAQAPLLSGPASGLPGDGDTLSFFSGAVESAFGLAQKVGTESQFASAGLAAAGPHGEASVAVGRNTDGAYTSRVT
GGTPANPLPVLPGGIAGPGEPEAGASPWGFVGSPVVRGHPPAHSFMPHPLIYTAQQCYGIQKPPLVERIPPLLEGASGTQ
AVGAKPEGGSGKSLAAKKSGVSARAWSPAGSVPGFSATEPDSGVSFDAPGRNDCVPFVAFRHSHNPAILPTMWTPDVFNK
TVIVDCPTLGLKIETVISIEVQTRSGVEGLEIRSTDASPKQGREASEGQDSRPQTNASLKTGVANAGEPQAGPPRHEGRE
AAARATVMEQTISACIWRFQVCAVRNCTWTVAALVLFDTEYAAVLRRTVGSVPGTPGAEAGDFGHGNTESHWQARGVESG
LGGLGMHDTRDHRAGGAGEVDVLDAVDNGLRHGTRRDNDQGGAYRGRPCHRSIDDWASRGPDAGRGAMGTYFGHAGSLAT
SSQSLSLHDTHGLTGVARGPGASPVDSATYVGSLHHVAGDGGSSGGGTGGRSSLAVSFVEGMDGSDGQGLHDDDDSSPAP
GDKIRFRLGTENVEGGSSRTPSPHSGAVTDSELGAGIGGRSRKSWLFRRTSAWLTGAGSTTGACGDRVGAGKRGGAALVE
EDVRAKRSSGRLRTLSSGPIRRFGGGSNPEGSSPAGGAPNTVAHPEGEGNLRKEGGKKARPIRPRSRSWFGRASDSELQY
LSSAGPGSSHFVSGDAGPMSPTNGVDDRTAVPPVHSKASAGESKTAWIRGRRPFRKGVKFYRQGVKDSVPQGRQHMPGGS
IATERPDASGVHAMSPRGVSPTPDGGAGTPGVGGPSGALGPSGGGAGKMMGAMGPHGSVLAYGTAGVGGLRVSGMVCEDA
TPGGTRRRPRTGRASGLGQEDAVGLPNGDLPGAWPGGLQPVHDSSYGPTWAPGGMRGGFCAYGGREGDWRMPDIAEAPGE
LEDDSGVLSVDEEVVSYVLQSFSVTVRRLAVWNVLYVSDDFPSFYSPSHPVSSEASMLPRSFDGHRDVSARRESSAGGTC
QIGVESLERPSPRGPSDWTFASSRQGSGGGSPQSKGTASANFGFSPEIRGKQLPPGAPAVPSLIVPPVRSAERLNFVASN
SFRHGEDSATQPSPGVALADSRGRKTVCHSSSATARGLGLHSWSGIHGHHVSVPFFLGGAGDHGVRSSVGFGEGRSSPLR
LLQSRHHPIFRGASHCHPAALASTAAFMGALGAAGHRGAAGFHPSLLHLGGVRRRSWMQAAAAPAGGPMADAALRHSRRN
TYQRRKDVSEMTVESVQRAIGGSVSSSVWEGRAGNARGPSVGLTATAGAWPGLGQDLQSAWPGDDAASFASHPDFPLELI
EANLRAQQAAANLVGVNLLLQELWCDDFVSMALPSVPFFAYAVAAQHLAPVLLPVVARTTSAGEQSFLRKQRDQEQQELK
RKQDELREQTLLYEQALRVRAQGKKGAGDKGPAASVGADRTLESIAAATAEVKRSNLASVRFDPATQSYTTRARSVREPD
SRRESSHLPDGGDAEKGADEASSRRGESSTKHGRSRAQDPHLTILFRLKDWENARAGRFTDADDKGEDNSMICKVSVHPT
FCSVDPFLMKTMVQLARPEGGLVGVLRRFQTEVTRVIQGHREAARDTSCRVSDAGRDTTTAGSWDHVSGQSPGRVHFGLE
VTETLSGKPRAAAPLLPENMKPTSVTGESDTDRERVGRLPVSPGRPAGDARSPGQSQGGAGAAEGDGQAKDKIGGPSAGT
KAAAEATVERVDHKLWGNSSQKLRAAAAFASTFLDHLPKSVFLSVAIESLQVSFPATTAVLAAAKVPVWVLPFPTRYLAV
PAHRIPLRAVPYYRLGCCSALSHTPTVCLDVIATLSCECKEDAEQRVANASPYGCSAHMQSDGGVSVPNSPAMANTGQGV
YVDSSQQASPAMYRPKGGSVPGPGFAHGHLGPGAHVPASGEQPVGSVLPGGSPYQRGTAEPYHGVQVRDGLLVPPIGGPV
LGRGSGQGVHPGKAHYGPVSLHWVPGGPRPSTGRARSFDEDGSWVPGGVEETGGLPGTTPTGNEIRDKFGGQGMGRAVPS
EVGSDSGGSLAGPLSLGFPVLRVQLLDQARMHDPAAPNSTQAVAAARTVVVMKTDAEVSGDNLSQPGRRPPSPKPQTTKF
PRRESPDRRGTRRRSESRGAVSRVWPGENQRRRSAVDDSIPANPIALNAWRPAILDVRVDRVEVTYTPVESDHNTDTGRV
EYGGTELLQGCLELSVGNVTVFTQDGSRLLRNTSSLRRLFSIPLSSSAPGGPGQATRSNPASPTPWWPQFGGAGGGRMSV
SGGPGIGRHGVPPPVTKKEAMRFGLSAMLAGRLEDRFIELCVRSSRFAVEAKGRVAMARVEAQIGHLVGCVDWVFLLADF
FKQQQKAETMYPAIDFGCCFSTAMFLSGEGVKNLLSEQICLVEANLAAEERLEFTTTGSTEVVGAGDRVDGHEALLRARS
SRLSDSSEFFGNLEEFERNSAVGRSAEGVGEDLFLSPDAGRDNMSGRAFDGSDDPSHGDDNHVEACLAGASDVRHRHEQQ
LQLLRMMKQARGLGLVKVMFPAFELPLDCTPLGDLVLPPLLPPLLPQEPVPHLPKDNRSGERMASFPHSTPVSEERASVW
GQGAQPDGERMWESPPNAVRYLQRMSTSGLLEHHDGKLKRLKSRQGWRLLGAKATPSAAAYNRAGPATAFSRKHSGGRLL
GPVLSLDESHPCSPNWIHRDRNCFPKGQEPLEDGRDRGSFIGRSDITPQLGDPGFFCRVGDGADDENEIRSDVPTDASAK
RGAPGGRRVGRDRLRKVVRIRGLFGRKKKNKASEASGHPLDFEEYSMEEDHDGEDDDQSSRLRFGSAGGSASIRTLRRPS
SLQTYRNHSMSGSMPKGFFFSRAQRNARRDQGPADGPTPPRAFDAMHAVCPPGILRHEEVGRPDLRFGAARHVPRYGDEQ
SHRHHEDCGVSGATVCSNTRGSCGSAAVSVPAFSKASTVAVLKGIREALAAAKKRSKHILTAGLPQRRKTVSVDLDGIEA
WIVLPPSDTAHRGSGAGAISGGGSYVGGSLGTGLGPSGGAEAGELSAVGGGKGPTSVHARTATCSTATPGAGDGSSKPLM
ESSEDRCGSALLPGGDPRSAVPVESASLSTNTTVESSGSSMMSCMSSGDTDSSSSSGSSLSDDDLLYSAMSPSVFSTGSM
LPRLQILSTAYKVAGFLLDEEQRENSKNRQTIAVGALVCCSLSVQQLGAEVSSGVRVRSLSVMIGTPTPSETVIDFVSPG
LSRYIHLPSFPGNAKWLTAAANSPPGVAGGSVSTFYGPPLGWTDGALAPSGWTAATGGGRCYYETGAHMGTAGRTQESGF
AVGGPAAVGLSDRGGLAAPAAQGQVAMSAAAGGFVQADAVNGGFDGTGTRGAAVNMAGAFERPVGGGPEFANAASTSGTR
AFVSGVSGNAKNPQARNTSLSSYGRAGPRLSRSSDEGWRVTLRGLPAVLEGFSGAVLLPNVHIRTDHLISISPSNLEFSG
VPGASGRVHLDINDPQVHFSFEIFQGLVEMHSRLEQEVASAKERIARNLCPSSQILSAVVAVQRIAEAATHVAAGTHGRG
TSVSSQLYFSQDVVVGSAGAGTQETLASQRHVAGDAGSSALSAGGSSRSSESGAVAGGQTDNAKFELVRVLYPHVCGRFI
TNYVVRMGDNSMEGQLLDVLAASLAGIPATGGHAPQARVAVLAYAPTMSKFGGSNGQGTTVEDLQKHVTKGVGIPRRTML
EFDSFERASSDSDSAHSGATEVKSPSGVREWDEASGAGGSLVHGTCLSHAGGVHSNWSGQRGDGDVVDLDGGHAPGTASH
QNSTMHLAGTKRSSASSVVIPGQQRETVVPTTTAGGSPASAGDSRPTTATTPAGGAPSGMSSVGFRLGSRASMEEGVSSY
GHAKGLGGREDGYLDEYSDEEEEAEDVPVVKIMEAVGVSPASVQAVGGGGACGPTAASVAPSVVAPSAGPSTAFGDASGY
FSWRGSAPDVERVPMIGEADAVGTSVLGQGAVEFSDPIHKMLDFLLALTQYKAEGETELDVHLGVRECTVEFHDSHGSLM
KVRILVVKGQTYIHPPVRGLNALKRFGARMEVMITGYDPMSNSQEEILHPLTAAVTMKREYSDPLVSDWSCLHIQASLGG
VSFDISSGLLQLVSYIINTGKEILDHEEGWLGTHNSLRVYNDLHTEILVMHKQRTRDKSKTWRYQKLLPNQWLVAPTSLL
FFSVRKYFPRESTGADDDSENDAGVWRSPSLHLNDEDDVRAFIDSLMALGTSRQKNQWLKAQERILLFASTRATQHPLEL
LAEDMPLLTGDGISPNDRTGSRTAAEQLLQLMRREPGWCNLGRLHADYSNCRCYCLHNAGYKVLVEPYVDRVRGVWSLTV
GSCVQIQNSCSMPLRIYEGRHRTYFQGVANSCCGRTGRLEWRRTDLGNFIDIMPQSRRSVPLSWFETGRLPGFAPLVEPD
ASLDVLWRMKEEENRPYGARAWTGHGDTSLPPVPFYALHKLLNQKNPGDNRRLALPPFTLQPRGILMFHGSVDVTDVPSQ
HTNRIAHKYVVKIEPMLTIKNTLPFHISIRLSVRNSQQNHRGARGRRRAAQGSLESGLEGSAIRGLHTDTKPDATGPGLG
AGLLGLPRPGRGEAGGSGLGAQDSGKGGVGSGDPRGSTGAGRLLGDRTDRERDVGKTPESFDNWGERGREEKGRSGGEAR
MIAPFGGAGGKSNLMLDRRRRGKQTDAMKLLSNKWVKAKIAPHEVWGIPVSEQRLYMKVSVHGAPLEIFETKPLPAEFIN
EVQNFISPLRSKHAGGGSSGGDVENTAAPQGRRGSGATEHLFHQPSRRKTYFHQGPRMVYESSRFSVFLPHQETVTVSRV
LYHRRGNLRALLPESARRLALADLGIIAGRKHRGRAAGLDMYAQMQVAADVSRRQVTIFSPYFFENLTDATLAINGLIVP
SKCRLYSTEEDAKNLILKVFKVDPLSNQILHTHLSKRMDLTGISTARLPLSLRFSPVKRNRGLRFGWGKRRAEATGASTS
SLPDRQVFRGGEILSAEKLRPLWEDADLSEGRDKDSDGLQTVVHSAFNDHWHEQDSPQERSLTEDAQSDWTYTESLEERT
DDKPEDSDDDDQAFSHSDSLSDGITGEQRERRAEGKTGVGVGSARTHDVPGGRRARAFRDRLMRRGRDSFIRGKTRHSAA
SLGNRVPTNAQSPTWYSDGQDQDAQRENRSPLCLRGGAQSLSGGRPGSSGEDSRANEGVGKAGRRRSKRSRLLSHIRRVE
ALQSLREQHGRMREQRERRPSRGEKVRIHATVPAPSERDDAVSVCETVQADWSGPAGAPSAVSVPVGAATAAAEKGTASA
GKIALWSGSTSIVMGCCTRYAELPYNTSKIVSFINRYEFVSQLPFPVLVRDVRAKSGVLGVMSARMKQRLCEMVLLPGQS
KAFHSMETKVTLTHPARTLTSLPFSLVPPHVPSSFQVELLPSTPAGAPAKGSSGATQPQRSLIVQVNIVSGLFGDVPALP
YTYNGLFLVLTIPSCPQFQICNLTRYCLAYLPGETTRQHRQHIQAEQAQEAQLNAAGTLGDQGGSQPSSVPISAGGAAET
GIGTHQLYPRGLGQSHIGVTAREGKLTNAGGVVSGARTSKGRPANGAGAAEKATAGMVTTARLVPPHSAVPYIPPVQKNI
ENVRVHLRVVDAQHCAWSTHCLANVVDHLQPIEFLPRRVAASTNGFEQGHLHDGGEDCRGIGTGMFQAGGQGASGSTADN
VSHIQSLSAGRQGHAPYTLLASPAQPTPSGSQQQLTALAALRSGAGEMGTASTGSLPLVLTSQRPGSYHSGHAVTSIPAS
TLHLSPPPPTSATTLSIVTTSHMSPRSQQPRFTPPGASLAEASGAGGAAWAYRSGPALSTVGAPVSDGAFYLASAPNGVG
PQPSPGMVTPTISAIPGVCGERHRVGATVLGGPEGPGEGSLLGIADYTDVATQVELTPRRRVKISEQRLAATAESPVTAV
SFVSAPSAPPPQHSTSQAAPVQRKKLWTFLIVSNTGSRLLMVCESRRMAHKVRSGLADFGEHLGFPQTAGTANSRIPSQK
YLTSSAVALYPGPEPLATGSTVLSPFDDIRSNGLWGRQPGAGGWESATSSRESLFKNLEEWMRSVPGEVYRADVASPLVI
SANSADLWFGHPANPARGPGLLELLMSLSKTDEDDGSGQGDALLGTCHGVSGRKASKKGKQKKKKQKKHADRDIVQRPPP
WLGLSYEFHLPRLTMTWIHQNEVVLALHMTNFSVAGGVMPKDTEAIFRAYPALIHTAEQKRKQVVMVPMRGIVHVSDLPE
FESRLWRRKQKRRRRRRRRREREGRGGSQGIGSGFDESGDELSEGDEHSESSGTEGGDLYGGRSTGVGGVGGVNGKGKKT
RGSHSSPPDFRTLLFTNSTASILLQISMLHLDHFVRGDIPVILKNTPPKDSKQKDVFLWFNVQRSLVDPRQAPMYDLIEL
KISSLSANIELLVIEQLIQLAEKEMQMLEVFQTTRQQVCPALQTALKCREAVKSILELNAVEKHWTHQHRGSSQPQHVAH
ALNVGAISGPSYTLNHPGGPSTVSTAGLTSGAILSASPLLGAAGMAAPAQQLLLSDQGLPGTGAVSGTQSGSQGAVTGAA
SALGGAQQSESLDQVWRHLPLQLQYYCEPRILISTKDSHVFVYPNPRWVELQDAAPIYLKHLRIAPMDLTVSIRTSEHRI
SRQVLHIVDALPLDTPYMSIQIASEKRRFIVCSWDELFYSLRNSYMRQFIRQSLPSAWMSNPFAFAMGFIRGCGALVGQT
VKGATSGGNVFEGLVTGFRIGFILFIIYTMGGIMQSLSHILNILHKLLGGSRPRPYGVLDAFWKGFNGFLLDTFWRPWVG
IATEPIASVNRGDSCPKTTAILCICLLRCIFSPVFGILNFLTSVTEGFSNTLIGDFEQFTRVQERADLGKKHKQVPQHGR
RSRTGSMLDVSGGFLGAPSSPGSTASPSASFGTSLVSTAGRGSIGFMSRGMPYFGAGGQVSGGGGDRGDGAGVVGDWGRL
NNASPAIGDGVVRGGRDSRGFFEVAVPKRGRQSRDSFAGAGEVQGGRNRSLDTEGGRWREERRRRDTFGSKLTSAFRKMS
SSKQVTFAV

Gene-Specific Links for TGME49_032080

General Sub-Cellular Localisation Links

  • TargetP, prediction of signal peptides, as well as chloroplast and mitochondrial transit peptides
  • OrthoMCL, automatic clustering of orthologous groups of proteins