ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

No assigned gene identifier (MORN1)

Nothing has been found, a gene from Eimeria ascervulina

Compiled localisation
inner membrane complex during daughter cell formation
during not macrogamete
nuclear pole during proliferative microgametocyte
flagellar basal bodies during flagellate growth
adjacent to mitochondrion and electron dense collar during microgametogeny
anterior adjacent to mitochondria during free microgamete and mature microgametogeny

Who localised this protein by microscopy?

Ferguson, D. J., Sahoo, N., Pinches, R. A., Bumstead, J. M., Tomley, F. M., Gubbels, M. J.
MORN1 has a conserved role in asexual and sexual development across the apicomplexa. (2008 Apr, Eukaryot Cell) PubMed / full text
   more detail about this publication

inner membrane complex during daughter cell formation, during not macrogamete, nuclear pole during proliferative microgametocyte, flagellar basal bodies during flagellate growth, adjacent to mitochondrion and electron dense collar during microgametogeny, anterior adjacent to mitochondria during free microgamete and mature microgametogeny
  • "However, in the small schizonts of E. acervulina, it was easier to follow the morphological changes. It was observed that after fragmentation of the apicoplast (Fig. 3G), the individual small apicoplast reoriented to become associated with the nuclei located beneath the MORN1-positive plaques (Fig. 3H). In more tangential sections, the plaques appeared as closely packed, ring-like structures (Fig. 3I). As the daughters grow, the MORN1-positive rings appear to move over the nuclei (Fig. 3J) and end with strongly positive posterior staining, where the daughters remain connected to the residual cytoplasm (Fig. 3K and L). This strong labeling of the posterior ring was also confirmed in the late stages of merozoite formation in E. tenella by electron microscopy (Fig. 4F and G). However, with detachment and release of the mature merozoites, it appeared that the strong posterior staining was greatly reduced, although the nuclear pole was still stained (data not shown). .. Sexual development was studied across four coccidian species: T. gondii, E acervulina, E. tenella, and E. maxima. They developed in similar manners and varied only in size and the number of gametes formed. Therefore, coccidian sexual development will be represented in a combined description without differentiating between the species."
  • Microscopy type:
  • Microscopy method: polyclonal antibody to homologue
  • Strain:
  • Gene model mapping comments: A common gene for all genes not assigned to a gene model taken directly from publication
  • Localisation record: IMC during daughter cell formation, not during macrogamete, nuclear pole during proliferative microgametocyte, flagellar basal bodies during flagellate growth, electron dense collar and adjacent to mitochondrion during microgametogeny, anterior adjacent to mitochondria during mature microgametogeny and free microgamete
  • Other genes localised in this publication: MORN repeat protein, putative, phosphatidylinositol-4-phosphate 5-kinase, putative, membrane skeletal protein IMC1, enolase 2, enoyl-acyl carrier reductase, Nothing has been found, gi|50295339|gb|AY566297.1| Eimeria tenella enoyl-acyl carrier reductase (ENR) mRNA, complete cds, Nothing has been found

Orthology

OrthoMCL

This species does not currently exist in the OrthoMCL database.

Amino Acid Sequence

>A common gene for all genes not assigned to a gene model Nothing has been found

Proteomics

Found in:

Not found in:

Gene-Specific Links for A common gene for all genes not assigned to a gene model

General Sub-Cellular Localisation Links

  • TargetP, prediction of signal peptides, as well as chloroplast and mitochondrial transit peptides
  • OrthoMCL, automatic clustering of orthologous groups of proteins