ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Schizont

Proteins expressed during this time are known in Plasmodium falciparum, Plasmodium yoelii, Plasmodium berghei, Plasmodium vivax, Toxoplasma gondii, Theileria annulata, Theileria parva, Theileria lestoquardi, Plasmodium gallinaceum, Eimeria tenella.

The schizont umbrella developmental stage includes proteins described as being expressed at: rupturing schizont, schizont, early schizont, mature schizont, segmented schizont, segmenter, after parasitophorous vacuole membrane breakdown, late blood stages, mature second generation schizont, middle schizont, mature schizont merozoite, macroschizont, 40 hours after merozoite invasion, late schizont, very late post-mitotic schizont, after trophozoite, mature first generation schizont, multinucleate mid-stage schizont, mid stage schizont, early- to mid- stage schizont

Toxoplasma gondii

Plasmodium berghei

Theileria annulata

  • TA14920 (HSP70, mthsp70) heat shock protein HSP70 homologue, putative
  • TA03135 (SuAT1) Tash(AT)-like protein, putative
  • TA06730 (CRK3) cdc2-like kinase
  • TA06510 (-gp34) hypothetical protein
  • TA17315 (PIM) surface protein precursor (TaSP), putative

Theileria parva

Plasmodium yoelii

  • PY02159 (P140, RON4) Drosophila melanogaster CG15040 gene product
  • PY04499 (LISP1) hypothetical protein
  • PY00409 (MTIP) myosin A tail domain interacting protein MTIP
  • PY01232 (MyoA) myosin A
  • PY06644 (enolase) enolase
  • PY05977 (MAEBL) erythrocyte binding protein
  • PY05748 (MSP-1, MSP1) merozoite surface protein 1 precursor
  • PY01581 (AMA1) apical membrane antigen-1
  • PY00414 (2-Cys Prx) thioredoxin peroxidase 1
  • PY04285 (1-Cys Prx) 1-cys peroxidoxin
  • PY04421 (HEP17, exp-1) U43539 hepatocyte erythrocyte protein 17 kDa
  • PY01365 (PY01365) rhoptry protein
  • PY04764 (EBL) duffy receptor, beta form precursor

Plasmodium vivax

Plasmodium falciparum

  • PFL1090w (GAP45) glideosome-associated protein 45
  • PFL2225w (MTIP) myosin A tail domain interacting protein
  • PF10_0168-b (GRASP, GRASP1) golgi re-assembly stacking protein 1
  • PFD0810w (Sar1p, Sar1) small GTP-binding protein sar1
  • PFD0895c (Bet3p) Bet3 transport protein, putative
  • PF11_0461 (Rab6) Rab GTPase 6
  • PF11_0171 (Sec12) ER membrane protein Sec12
  • PF13_0324 (Sec24a) Sec24 subunit a
  • PFI0875w (grp, Hsp70-2, BiP) heat shock protein 70
  • PFB0640c (Sec31, Sec31p) sec31p
  • PF13_0280 (ERD2) ER lumen protein retaining receptor
  • PFI0880c (GAP50, SAP) glideosome-associated protein 50,secreted acid phosphatase
  • PF10_0281 (MTRAP) merozoite TRAP-like protein
  • PFB0340c (SERA5, SERP, p126, SERA, pl26) serine repeat antigen 5
  • PF14_0102 (RAP-1 p86, RAP-1 p82, RAP-1 p67, RAP1, RAP-1) rhoptry-associated protein 1
  • MAL13P1.231 (Sec61) Sec61 alpha subunit, PfSec61
  • MAL7P1.27 (CRT) chloroquine resistance transporter
  • PFE0065w (SBP1, SBP) skeleton-binding protein 1
  • MAL13P1.413 (MAHRP-1, MAHRP1, MAHRP) membrane associated histidine-rich protein
  • PFL1465c (HslV) heat shock protein hslv
  • PFC0890w (Sec22) SNARE protein
  • PF13_0322 (FLN) falcilysin
  • PFB0385w (ACP) acyl carrier protein
  • PF10_0153 (Cpn60, Hsp60, hsp60) heat shock protein 60
  • MAL13P1.220 (LipA) lipoate synthase, putative
  • PF13_0083 (LplA) lipoate protein ligase a type 1
  • PFL2210w (ALAS) delta-aminolevulinic acid synthetase
  • PF14_0381 (PGBS, ALAD) delta-aminolevulinic acid dehydratase
  • PFL0480w (HMBS, PBGD) porphobilinogen deaminase
  • PF14_0382 (SPP) stromal-processing peptidase, putative
  • PFD1105w (AARP) asparagine-rich protein
  • PFC0110w (CLAG 3.1, RhopH1 3.1, Clag3.1) cytoadherence linked asexual protein 3.2
  • PFC0525c (GSK-3) glycogen synthase kinase 3
  • PF11_0506 (Pf332) antigen 332, DBL-like protein
  • PF13_0252 (NT1, ENT1) nucleoside transporter 1
  • PFB0210c (HT1) hexose transporter
  • PF11_0396 (PP2C) protein phosphatase 2c
  • PFD0100c (surf4.1) surface-associated interspersed gene 4.1, (SURFIN4.1)
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • MAL7P1.176 (EBA-175, EBA175) erythrocyte binding antigen-175
  • PF10_0306 (MORN1) MORN repeat protein, putative
  • PF10_0155 (enolase) enolase
  • PFI0450c (ARP) apoptosis-related protein, putative
  • PFI0050c (RIFIN) rifin
  • MAL13P1.214 (pmt) phosphoethanolamine N-methyltransferase
  • PFL0620c (Gatp) glycerol-3-phosphate acyltransferase
  • PFA0445w (CCp5) LCCL domain-containing protein
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PFL0740c (Cpn10) 10 kd chaperonin
  • PF13_0180 (Cpn20) cochaperonin
  • MAL7P1.150 (IscS) cysteine desulfurase, putative
  • PFL1545c (Cpn60-2) chaperonin, cpn60
  • PF11_0165 (Falcipain-2, FP2) cysteine proteinase falcipain 2a
  • PF11_0162 (Falcipain-3, FP3) cysteine proteinase falcipain 3
  • PF08_0066 (aLipDH) lipoamide dehydrogenase
  • PFL1550w (mLipDH) lipoamide dehydrogenase
  • PF13_0152 (Sir2) transcriptional regulatory protein sir2a
  • PFE0150c (IspE) 4-diphosphocytidyl-2c-methyl-D-erythritol kinase (CMK), putative
  • PF10_0218 (CS, CSP, citrate synthase) citrate synthase, mitochondrial precursor, putative
  • PFI1730w (CLAG9) cytoadherence linked asexual protein 9
  • PFI0265c (RhopH3, Rhop-3) high molecular weight rhoptry protein 3
  • PFC0380w (YVH1) dual specificity phosphatase
  • PFB0095c (EMP3) erythrocyte membrane protein 3
  • PFB0100c (KAHRP, HRP1) knob-associated histidine-rich protein
  • PF11_0486 (MAEBL) merozoite adhesive erythrocytic binding protein
  • MAL13P1.60 (EBA140, EBA-140, BAEBL) erythrocyte binding antigen-140
  • PFI1445w (RhopH2) high molecular weight rhoptry protein 2
  • PFF1105c (chorismate synthase, CS) chorismate synthase
  • MAL13P1.185 (PK6) protein kinase 6
  • PFA0410w (ARP) conserved Plasmodium protein, unknown function
  • PF11_0381 (SUB2) subtilisin-like protease 2
  • PFI1260c (HDAC1) histone deacetylase
  • PF11_0225 (GCN20) ABC transporter GCN20
  • PFB0310c (MSP-4, MSP4) merozoite surface protein 4
  • PFF1370w (PK4) protein kinase PK4
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • PFA0125c (EBA-181, JSEBL, EBA181) erythrocyte binding antigen-181
  • PFD0295c (ASP) apical sushi protein
  • PFL0870w (PTRAMP) thrombospondin-related apical membrane protein
  • PFB0935w (CLAG2) cytoadherence linked asexual protein 2
  • PFE0080c (RAP2) rhoptry-associated protein 2
  • PFE0395c (Pf38) 6-cysteine protein
  • PFF0615c (Pf12) 6-cysteine protein
  • PFD0240c ( 41, Pf41) 6-cysteine protein
  • PFF0995c (MSP-10) merozoite surface protein 10
  • PF10_0343 (S-antigen) S-antigen
  • PF10_0344 (GLURP) glutamate-rich protein
  • PF13_0197 (p22, MSP7) merozoite surface protein 7 precursor
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • PF10_0345 (MSP3.1, MSP3) merozoite surface protein 3
  • PF10_0346 (MSP-6 36, MSP3.2, MSP6) merozoite surface protein 6
  • PFL1385c (ABRA, MSP9, MSP-9) merozoite surface protein 9
  • PFE0370c (SUB1) subtilisin-like protease 1
  • PFA0110w (RESA) ring-infected erythrocyte surface antigen
  • PFB0345c (SERA4, SERA3) serine repeat antigen 4
  • PFB0335c (SERP H, SERA6, SERP-H) serine repeat antigen 6
  • MAL7P1.208 (RAMA p60, RAMA) rhoptry-associated membrane antigen
  • PFD1145c (Rh5, RH5) reticulocyte binding protein homologue 5
  • PF11_0168 (RON4, Pf225) rhoptry neck protein 4
  • PF13_0198 (RpfR2Hb, RBP-Ha, Rh2a, NBP2a) reticulocyte binding protein 2 homologue a
  • MAL13P1.176 (RpfR2Ha, RBP-Hb, Rh2b, NBP2b) reticulocyte binding protein 2 homologue b
  • PFB0300c (MSP-2, Ag513) merozoite surface protein 2
  • PF10_0352 (H103, MSP3.6) merozoite surface protein
  • PF13_0348 (Rhop148) rhoptry protein
  • PFE0340c (Rom-4) rhomboid protease ROM4
  • PFE0120c (MSP-8) merozoite surface protein 8,ring-stage membrane protein 1
  • No assigned gene identifier (EBL-1)
  • MAL7P1.119 (RALP1) rhoptry-associated leucine zipper-like protein 1
  • PFL0150w (Orc1, ORC1) origin recognition complex subunit 1
  • PFF0530w (Tk) transketolase
  • PFL1315w (K1, pfkch1) potassium channel protein
  • PF14_0622 (K2) potassium channel protein
  • PFE0040c (MESA, EMP2) mature parasite-infected erythrocyte surface antigen,erythrocyte membrane protein 2
  • PF10_0368 (DYN2) dynamin-like protein
  • PF13_0085 (UBC13) serine/threonine protein kinase
  • PF11_0224 (exp-1, EXP1, EXP-1) circumsporozoite-related antigen
  • PFI0580c (Falstatin) falstatin
  • PFL0145c (HMGB1) high mobility group protein
  • MAL8P1.72 (HMGB2) high mobility group protein
  • PFE1195w (Kb) karyopherin beta
  • PFL0565w (j4) heat shock protein DNAJ homologue Pfj4
  • PFI0930c (NAPS, NapS) nucleosome assembly protein
  • PFL0185c (NAPL) nucleosome assembly protein
  • PFL2275c (FKBP35) FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
  • PF08_0129 (CnA) serine/threonine protein phosphatase, putative
  • PF13_0080 (TERT) telomerase reverse transcriptase, putative
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PF11_0174 (DPAP1) cathepsin C, homolog,dipeptidyl peptidase 1
  • PF14_0652 (D13) conserved Plasmodium protein, unknown function
  • PFE0690c (Rab1A) Rab GTPase 1a
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PF11_0098 (ERC, ERC1, Pfs40, Pf39) endoplasmic reticulum-resident calcium binding protein
  • PF10_0159 (GBP130) glycophorin binding protein
  • PFE0175c (MyoB) myosin B
  • MAL13P1.122 (SET2) SET domain protein, putative
  • PF13_0293 (SET6) histone-lysine N-methyltransferase, putative
  • PFL0575w (LSD1) lysine-specific histone demethylase 1, putative
  • PFL1010c conserved Plasmodium protein, unknown function
  • PF08_0012 (KMT1, SET3) SET domain protein, putative
  • PFI0250c (Nup100) conserved Plasmodium membrane protein, unknown function
  • PFL1435c (MyoD) myosin D
  • PFE0285c (SUMO) small ubiquitin-related modifier, putative
  • PF10_0395 (STEVOR) stevor
  • PFD1165w (FIKK4.1) serine/threonine protein kinase, FIKK family
  • PFI0105c (FIKK9.3) serine/threonine protein kinase, FIKK family
  • PFI0120c (FIKK9.6) serine/threonine protein kinase, FIKK family
  • PFC0160w (AnkDHHC) palmitoyl transferase
  • PFD1150c (RH4) reticulocyte binding protein homologue 4
  • PFD0110w (NBP-1, Rh1) normocyte binding protein 1,reticulocyte binding protein homologue 1
  • PF13_0133 (PM V, PM5, PMV) plasmepsin V
  • PF11_0139 (PRL, EP) protein tyrosine phosphatase
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • PF14_0016 (SEP14) early transcribed membrane protein 14.1
  • PF11_0040 (SEP11.1) early transcribed membrane protein 11.2
  • PFD1120c (ETRAMP4, SEP4, Etramp 4, Etramp4) early transcribed membrane protein 4
  • PFI1160w (LplA2) lipoate protein ligase a type 2
  • PFB0505c (FabH) beta-ketoacyl-ACP synthase III
  • PFF1130c (SOD2) superoxide dismutase
  • PF14_0495 (RON2) rhoptry neck protein 2
  • PFB0480w (Stx1) syntaxin, Qa-SNARE family
  • PFB0680w (RON6) rhoptry neck protein 6
  • PFD0955w (Pf34, Pf-34) apical merozoite protein
  • PFF0775w (PdxK) pyridoxine kinase
  • MAL8P1.3 (25-IMP) Plasmodium exported protein (hyp9), unknown function
  • PFL1005c (HP1, H1) heterochromatin protein 1
  • PFF0510w (H3, h3k9m3, h3k9ac, H3K9Me1, H3K9me3, H3K9ac) histone H3
  • PF14_0242 (PRMT1) arginine methyltransferase 1
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • PF10_0348 (DBLMSP, MSP3.7, H103) duffy binding-like merozoite surface protein
  • PF10_0347 (MSP3.3, H101) merozoite surface protein
  • PF10_0350 (MSP3.4) probable protein, unknown function
  • PF10_0355 (MSP3.8) merozoite surface protein
  • PFI0735c (NDH) type II NADH:quinone oxidoreductase
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PF14_0498 (sDer1-1, Der1-Pl) DER1-like protein
  • PF14_0653-a (hDer1-1) derlin-1
  • PF14_0653-b derlin-1
  • PF13_0182 (sUba1) ubiquitin-activating enzyme
  • PFB0190c (Sel1) conserved Plasmodium protein, unknown function
  • PF14_0462 (Sel2) ubiquitin-protein ligase, putative
  • PF11_0220 (EK) protein kinase
  • PF14_0344 (PTEX150) translocon component PTEX150
  • PF11_0175 (HSP101, ClpB2) heat shock protein 101
  • MAL13P1.130 (GAPM1) glideosome associated protein with multiple membrane spans 1
  • PFD1110w (GAPM2) glideosome associated protein with multiple membrane spans 2
  • PF14_0065 (GAPM3) glideosome associated protein with multiple membrane spans 3, putative
  • PF14_0112 (PREX) plastid replication-repair enzyme
  • PF14_0294 (map-1) mitogen-activated protein kinase 1
  • PFI0550w (CRMP1) cysteine repeat modular protein 1
  • MAL7P1.92 (CRMP2) cysteine repeat modular protein 2
  • PFC0140c (NSF) N-ethylmaleimide sensitive fusion protein, putative
  • PF13_0328 (PCNA, PCNA1) proliferating cell nuclear antigen
  • PFB0720c (ORC5) origin recognition complex subunit 5
  • PFA0345w-b (CEN1) centrin-1
  • PF14_0443 (CEN2) centrin-2
  • PF10_0271 (CEN3) centrin-3
  • PF11_0066 (CEN4) centrin-4
  • PFI0180w (A-tubulin) alpha tubulin 1
  • PFL1410c (MRP2) ABC transporter, (CT family)
  • PF13_0218 (MDR5) ABC transporter (MDR family), putative
  • PFE0420c (RCC1) guanidine nucleotide exchange factor
  • MAL7P1.91 (FEST) exported serine/threonine protein kinase
  • MAL13P1.310 (calpain) calpain
  • PF14_0020 (CK) choline kinase
  • PF11_0257 (EK) ethanolamine kinase, putative
  • PF14_0368 (TPx-1) thioredoxin peroxidase 1
  • PF08_0131 (1-Cys-Prx) 1-cys peroxiredoxin
  • PF14_0545 (Trx-1) thioredoxin, putative
  • PFL0725w (pftrx-px2, TPx-2) thioredoxin peroxidase 2
  • PFI1570c (DAP, M18AAP) M18 aspartyl aminopeptidase
  • PFA0330w (AARP2) small ribosomal subunit assembling AARP2 protein
  • PF08_0108 (PM X) plasmepsin X
  • PFD0230c dipeptidyl peptidase 3
  • PFD1130w conserved Plasmodium protein, unknown function
  • PF10_0119 conserved Plasmodium protein, unknown function
  • PF10_0166 conserved Plasmodium protein, unknown function
  • PF10_0295 conserved Plasmodium protein, unknown function
  • PF14_0119 p1/s1 nuclease, putative
  • PF14_0572 conserved Plasmodium membrane protein, unknown function
  • PFL0300c protein phosphatase, putative
  • MAL13P1.94 conserved Plasmodium membrane protein, unknown function
  • PFD0720w conserved ARM repeats protein, unknown function
  • PF10_0156 conserved Plasmodium protein, unknown function
  • PF10_0223 conserved Plasmodium membrane protein, unknown function
  • PFL2085w conserved Plasmodium protein, unknown function
  • PF13_0125 conserved Plasmodium protein, unknown function
  • PFB0475c conserved Plasmodium protein, unknown function
  • PFD0705c conserved protein, unknown function
  • PFI1015w conserved Plasmodium protein, unknown function
  • PF11_0166 conserved Plasmodium protein, unknown function
  • PFC0355c conserved Plasmodium protein, unknown function
  • PFE1285w membrane skeletal protein IMC1-related
  • PF10_0039 membrane skeletal protein IMC1-related
  • PFE1130w conserved protein, unknown function
  • PF14_0578 conserved Plasmodium protein, unknown function
  • MAL13P1.228 conserved Plasmodium protein, unknown function
  • PFE0910w conserved Plasmodium protein, unknown function
  • PFI1565w profilin, putative
  • PF11_0190 haloacid dehalogenase-like hydrolase, putative
  • PF14_0092 conserved Plasmodium membrane protein, unknown function
  • PF14_0222 ankyrin, putative
  • PF14_0369 copper transporter putative
  • MAL13P1.215 conserved Plasmodium protein, unknown function
  • MAL8P1.79 conserved Plasmodium protein, unknown function
  • PFL2100w ubiquitin conjugating enzyme E2, putative
  • PFC0945w protein kinase, putative
  • PFL1480w (Sec13p) protein transport protein Sec13, putative
  • PFI1755c (REX3, Rex3) ring-exported protein 3
  • PF11_0145 (GloI) glyoxalase I
  • PFD0311w (cGloII) cytosolic glyoxalase II
  • PFL0285w (tGloII) targeted glyoxalase II
  • PFF0200c (SIP2) transcription factor with AP2 domain(s), putative,SPE2-interacting protein
  • PF10_0164 (ETRAMP10.3) early transcribed membrane protein 10.3
  • PF10_0141 (mrk) MO15-related protein kinase
  • PFE0610c (MAT1) CDK-activating kinase assembly factor
  • PFD0740w (crk-3) cdc2-related protein kinase 3
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • MAL8P1.46 (DLC1) dynein light chain 1
  • PF13_0233 (MyoA, -myo1) myosin A
  • PF11_0061 (H4, h4k5ac, H4K5Ac, H4K8Ac, H4Ac4) histone H4
  • PF13_0338 (Pf92) cysteine-rich surface protein
  • PF14_0201 (Pf113) surface protein, Pf113
  • MAL8P1.32 (NT2) nucleoside transporter 2
  • PFC0310c (ClpP) ATP-dependent Clp protease proteolytic subunit
  • PFE0435c (SSB) single-strand binding protein, putative
  • PF13_0258 (TKL3) serine/threonine protein kinase
  • PFC1050w (TSN, Tudor-SN) survival of motor neuron (SMN)-like protein
  • PF11_0192 (MYST) histone acetyltransferase, putative
  • PF08_0071 (SOD1) Fe-superoxide dismutase
  • PF14_0177 (MCM2) minchromosome maintenance (MCM) complex subunit
  • PF13_0291 (MCM6) minchromosome maintenance (MCM) complex subunit
  • PFE0555w (SCD) stearoyl-CoA delta 9 desaturase, putative
  • MAL8P1.17 (Pf52, PDI, DSI) protein disulfide isomerase
  • PFI0240c (CuP-ATPase) Cu2 -transporting ATPase, putative
  • PFI1735c (REX1) ring-exported protein 1
  • PFC0105w (SRPK1, CLK-4) serine/threonine protein kinase, putative
  • PFE0160c (SR1) Ser/Arg-rich splicing factor, putative
  • PF10_0168-a (GRASP2) golgi re-assembly stacking protein 2
  • PFB0200c (AspAT) aspartate aminotransferase
  • PF14_0534 (SHMTm) serine hydroxymethyltransferase, putative
  • PFL1720w (SHMTc) serine hydroxymethyltransferase
  • MAL13P1.279 (PK5, CDPK5) protein kinase 5
  • PFL2505c (RON3) conserved Plasmodium protein, unknown function
  • PF10_0268 (MCP-1, nPrx) merozoite capping protein 1
  • PF13_0095 (MCM4) minchromosome maintenance (MCM) complex subunit, putative
  • PF14_0408 (SRPK2, CLK-2) serine/threonine protein kinase, putative
  • PF14_0025 (Rpn6) proteosome subunit, putative
  • PFC0920w (H2A.Z) histone H2A variant, putative
  • PF14_0641 (Dxr) 1-deoxy-D-xylulose 5-phosphate reductoisomerase
  • PFF0860c (H2A) histone H2A

Plasmodium gallinaceum

  • DQ068022 (SES) gi|68521875|gb|DQ068022.1| Plasmodium gallinaceum SES mRNA, complete cds

Theileria lestoquardi

  • DQ004498 (clone-5) gi|63079800|gb|DQ004498.1| Theileria lestoquardi unknown protein long splice variant mRNA, complete cds, alternatively spliced

Eimeria tenella

  • AJ306453 (MIC4) gi|187340650|emb|AJ306453.2| Eimeria tenella mRNA for microneme protein 4 (mic4 gene)
  • AY512381 (MIC3) gi|40549146|gb|AY512381.1|AY512381S1 Eimeria tenella microneme protein MIC3 gene, partial cds
  • AF042329 (Hsp90) gi|2792526|gb|AF042329.1| Eimeria tenella heat shock protein 90 (hsp90) mRNA, complete cds
  • AF353515 (Enolase) gi|13774514|gb|AF353515.1| Eimeria tenella enolase mRNA, complete cds
  • AY566297 (ENR) gi|50295339|gb|AY566297.1| Eimeria tenella enoyl-acyl carrier reductase (ENR) mRNA, complete cds