ApiLoc - A database of published protein sub-cellular localisation in Apicomplexa

version 3 (curated until May 28, 2011)

Merozoite

Proteins expressed during this time are known in Plasmodium falciparum, Plasmodium knowlesi, Plasmodium yoelii, Plasmodium berghei, Plasmodium vivax, Plasmodium chabaudi, Toxoplasma gondii, Babesia bovis, Cryptosporidium parvum, Sarcocystis neurona, Babesia divergens, Babesia equi, Babesia gibsoni, Babesia bigemina, Babesia microti, Eimeria maxima, Eimeria tenella.

The merozoite umbrella developmental stage includes proteins described as being expressed at: first generation merozoite, invasion, after rupture, rupturing form, intracellular merozoite, early single intracellular merozoite, extracellular merozoite, merozoite, type i merozoite, early extracellular merozoite, second generation merozoite, individual merozoites, merozoite invasion, after microneme exocytosis, invading merozoite, early merozoite, newly invaded merozoite

Plasmodium chabaudi

  • PCHAS_000190 (Ag3008, Pc24) early transcribed membrane protein (ETRAMP)

Toxoplasma gondii

Plasmodium berghei

Plasmodium knowlesi

  • PKH_146970 (NBPXa) reticulocyte binding protein, putative (fragment)
  • PKH_146980 (NBPXb) reticulocyte binding protein, putative (fragment)
  • PKH_041300 (MSP-4, MSP4) merozoite surface protein, putative
  • PKH_041310 (MSP-5, MSP5) merozoite surface protein 5

Plasmodium yoelii

  • PY06415 (pAg-2) merozoite surface protein precursor
  • PY00409 (MTIP) myosin A tail domain interacting protein MTIP
  • PY01232 (MyoA) myosin A
  • PY04764 (EBL) duffy receptor, beta form precursor
  • PY01581 (AMA1) apical membrane antigen-1

Plasmodium vivax

Babesia bovis

Cryptosporidium parvum

  • cgd6_4840 (SUB1) serine protease, subtilase family, signal peptide
  • cgd6_780 (MIC1, TSP8) CpTSP8,predicted extracellular protein with 3 TSP1 repeats, an EGF domain and a C-terminal transmembrane domain. adjacent TSP domain containing gene.
  • cgd6_1080 (gp40/15, gp15, gp-15, GP15, GP40, gp40) conserved hypothetical protein
  • cgd7_4020 (GP900, gp900) cryptopsoridial mucin, large thr stretch, signal peptide sequence

Plasmodium falciparum

  • PFL1090w (GAP45) glideosome-associated protein 45
  • PFI0880c (GAP50, SAP) glideosome-associated protein 50,secreted acid phosphatase
  • PFL2225w (MTIP) myosin A tail domain interacting protein
  • PF13_0233 (MyoA, -myo1) myosin A
  • PF10_0168-b (GRASP, GRASP1) golgi re-assembly stacking protein 1
  • PFD0810w (Sar1p, Sar1) small GTP-binding protein sar1
  • PFD0895c (Bet3p) Bet3 transport protein, putative
  • MAL13P1.413 (MAHRP-1, MAHRP1, MAHRP) membrane associated histidine-rich protein
  • PFD1105w (AARP) asparagine-rich protein
  • PFI1475w (MSP1, MSP-1, msp1 unprocessed, msp1, Msp-1 19, MSP1 19) merozoite surface protein 1
  • PF11_0344 (AMA-1, AMA1) apical membrane antigen 1
  • MAL7P1.176 (EBA-175, EBA175) erythrocyte binding antigen-175
  • PFC0110w (CLAG 3.1, RhopH1 3.1, Clag3.1) cytoadherence linked asexual protein 3.2
  • PFD0100c (surf4.1) surface-associated interspersed gene 4.1, (SURFIN4.1)
  • PFD1160w (SURFIN4.2, Surf4.2) surface-associated interspersed gene 4.2, (SURFIN4.2)
  • PF10_0155 (enolase) enolase
  • PFD0305c (Vacuolar ATP H+ Synthase subunit b) vacuolar ATP synthase subunit b
  • PF11_0313 (P0) 60S ribosomal protein P0
  • PF11_0486 (MAEBL) merozoite adhesive erythrocytic binding protein
  • MAL13P1.60 (EBA140, EBA-140, BAEBL) erythrocyte binding antigen-140
  • PF14_0102 (RAP-1 p86, RAP-1 p82, RAP-1 p67, RAP1, RAP-1) rhoptry-associated protein 1
  • PFI1445w (RhopH2) high molecular weight rhoptry protein 2
  • PF11_0381 (SUB2) subtilisin-like protease 2
  • PFF1370w (PK4) protein kinase PK4
  • PFA0125c (EBA-181, JSEBL, EBA181) erythrocyte binding antigen-181
  • PFL0870w (PTRAMP) thrombospondin-related apical membrane protein
  • PFE0080c (RAP2) rhoptry-associated protein 2
  • MAL13P1.176 (RpfR2Ha, RBP-Hb, Rh2b, NBP2b) reticulocyte binding protein 2 homologue b
  • PF13_0198 (RpfR2Hb, RBP-Ha, Rh2a, NBP2a) reticulocyte binding protein 2 homologue a
  • PF13_0338 (Pf92) cysteine-rich surface protein
  • PFE0395c (Pf38) 6-cysteine protein
  • PFF0615c (Pf12) 6-cysteine protein
  • PFD0240c ( 41, Pf41) 6-cysteine protein
  • PFF0995c (MSP-10) merozoite surface protein 10
  • MAL7P1.208 (RAMA p60, RAMA) rhoptry-associated membrane antigen
  • PF10_0344 (GLURP) glutamate-rich protein
  • PF10_0345 (MSP3.1, MSP3) merozoite surface protein 3
  • PFL1385c (ABRA, MSP9, MSP-9) merozoite surface protein 9
  • PF13_0197 (p22, MSP7) merozoite surface protein 7 precursor
  • PFE0370c (SUB1) subtilisin-like protease 1
  • PFD0110w (NBP-1, Rh1) normocyte binding protein 1,reticulocyte binding protein homologue 1
  • PFD1145c (Rh5, RH5) reticulocyte binding protein homologue 5
  • PF11_0168 (RON4, Pf225) rhoptry neck protein 4
  • PFB0305c-a (MSP-5) merozoite surface protein 5
  • PF10_0346 (MSP-6 36, MSP3.2, MSP6) merozoite surface protein 6
  • PFE0120c (MSP-8) merozoite surface protein 8,ring-stage membrane protein 1
  • MAL7P1.119 (RALP1) rhoptry-associated leucine zipper-like protein 1
  • PFI1730w (CLAG9) cytoadherence linked asexual protein 9
  • PF14_0543 (SPP) signal peptide peptidase
  • PFI0580c (Falstatin) falstatin
  • PFI0930c (NAPS, NapS) nucleosome assembly protein
  • PFL0185c (NAPL) nucleosome assembly protein
  • PF14_0652 (D13) conserved Plasmodium protein, unknown function
  • PF13_0119 (Rab11A, Rab11) Rab GTPase 11a
  • PFA0110w (RESA) ring-infected erythrocyte surface antigen
  • PFE0175c (MyoB) myosin B
  • PFD1150c (RH4) reticulocyte binding protein homologue 4
  • PFB0815w (CDPK1) calcium dependent protein kinase 1
  • MAL7P1.27 (CRT) chloroquine resistance transporter
  • PFL1885c (PK2) protein kinase 2
  • PFI1160w (LplA2) lipoate protein ligase a type 2
  • PFB0385w (ACP) acyl carrier protein
  • PF14_0495 (RON2) rhoptry neck protein 2
  • PFB0680w (RON6) rhoptry neck protein 6
  • PFL2250c (PKB) RAC-beta serine/threonine protein kinase
  • PF10_0348 (DBLMSP, MSP3.7, H103) duffy binding-like merozoite surface protein
  • PFI0735c (NDH) type II NADH:quinone oxidoreductase
  • PFE1545c (Formin1) formin 1, putative
  • PFA0590w (MRP, MRP1) ABC transporter, (CT family), putative
  • PFD0255w (mag-1) ag-1 blood stage membrane protein homologue
  • PFB0310c (MSP-4, MSP4) merozoite surface protein 4
  • PF14_0346 (PKG) cGMP-dependent protein kinase
  • PF08_0108 (PM X) plasmepsin X
  • PFD0230c dipeptidyl peptidase 3
  • PFB0570w (SPATR) secreted protein altered thrombospondin repeat protein
  • PFD1130w conserved Plasmodium protein, unknown function
  • PF10_0119 conserved Plasmodium protein, unknown function
  • PF10_0166 conserved Plasmodium protein, unknown function
  • PF10_0295 conserved Plasmodium protein, unknown function
  • PF14_0119 p1/s1 nuclease, putative
  • PF14_0572 conserved Plasmodium membrane protein, unknown function
  • PFL0300c protein phosphatase, putative
  • MAL13P1.94 conserved Plasmodium membrane protein, unknown function
  • PFD0720w conserved ARM repeats protein, unknown function
  • PF10_0156 conserved Plasmodium protein, unknown function
  • PF10_0223 conserved Plasmodium membrane protein, unknown function
  • PFL2085w conserved Plasmodium protein, unknown function
  • PF13_0125 conserved Plasmodium protein, unknown function
  • PFB0475c conserved Plasmodium protein, unknown function
  • PFD0705c conserved protein, unknown function
  • PFI1015w conserved Plasmodium protein, unknown function
  • PF10_0352 (H103, MSP3.6) merozoite surface protein
  • PF11_0166 conserved Plasmodium protein, unknown function
  • PFC0355c conserved Plasmodium protein, unknown function
  • MAL13P1.130 (GAPM1) glideosome associated protein with multiple membrane spans 1
  • PFE1285w membrane skeletal protein IMC1-related
  • PF10_0039 membrane skeletal protein IMC1-related
  • PFE1130w conserved protein, unknown function
  • PFD1110w (GAPM2) glideosome associated protein with multiple membrane spans 2
  • PF14_0578 conserved Plasmodium protein, unknown function
  • MAL13P1.228 conserved Plasmodium protein, unknown function
  • PFE0910w conserved Plasmodium protein, unknown function
  • PFI1565w profilin, putative
  • PF11_0190 haloacid dehalogenase-like hydrolase, putative
  • PF14_0092 conserved Plasmodium membrane protein, unknown function
  • PF14_0222 ankyrin, putative
  • PF14_0369 copper transporter putative
  • MAL13P1.215 conserved Plasmodium protein, unknown function
  • MAL8P1.79 conserved Plasmodium protein, unknown function
  • PFL2100w ubiquitin conjugating enzyme E2, putative
  • PFC0945w protein kinase, putative
  • PFL0285w (tGloII) targeted glyoxalase II
  • MAL8P1.73 (RON5) rhoptry neck protein 5, putative
  • PF14_0598 (pfGAPDH) glyceraldehyde-3-phosphate dehydrogenase
  • PF14_0425 (aldolase, pfAldolase) fructose-bisphosphate aldolase
  • PF11_0061 (H4, h4k5ac, H4K5Ac, H4K8Ac, H4Ac4) histone H4
  • PFF0510w (H3, h3k9m3, h3k9ac, H3K9Me1, H3K9me3, H3K9ac) histone H3
  • PF10_0268 (MCP-1, nPrx) merozoite capping protein 1
  • PFI0265c (RhopH3, Rhop-3) high molecular weight rhoptry protein 3
  • PF10_0168-a (GRASP2) golgi re-assembly stacking protein 2
  • PFF1105c (chorismate synthase, CS) chorismate synthase
  • MAL13P1.279 (PK5, CDPK5) protein kinase 5
  • PFF0860c (H2A) histone H2A

Sarcocystis neurona

  • AF532594 (MIC10) gi|22347778|gb|AF532594.1| Sarcocystis neurona microneme antigen 10 (MIC10) mRNA, complete cds
  • AY325815 (NTP1) gi|32816823|gb|AY325815.1| Sarcocystis neurona nucleoside triphosphate hydrolase (NTP) mRNA, complete cds

Babesia bigemina

  • AF142406 (p200) gi|7549209|gb|AF142406.1| Babesia bigemina 200 kDa antigen p200 mRNA, partial cds

Babesia divergens

  • EU219619 (Bd17, BDHSP20) gi|164710611|gb|EU219619.1| Babesia divergens HSP-20 (hsp-20) mRNA, complete cds

Babesia gibsoni

  • DQ386864 (RAP-1a) gi|88770793|gb|DQ386864.1| Babesia gibsoni rhoptry-associated protein mRNA, complete cds
  • AB480715 (RAP-1b) gi|255708245|dbj|AB480715.1| Babesia gibsoni BgRAP-1b mRNA for rhoptry-associated protein-1b, complete cds
  • AB480716 (RAP-1c) gi|255708247|dbj|AB480716.1| Babesia gibsoni BgRAP-1c mRNA for rhoptry-associated protein-1c, complete cds
  • AB051834 (P50) gi|14646758|dbj|AB051834.1| Babesia gibsoni P50 mRNA, complete cds
  • FJ608703 (P22) gi|223036619|gb|FJ608703.1| Babesia gibsoni isolate BgP22 merozoite 22-kDa protein mRNA, partial cds
  • AB490782 (LAP) gi|253735627|dbj|AB490782.1| Babesia gibsoni BgLAP mRNA for leucine aminopeptidase, complete cds

Babesia equi

  • AB043618 (EMA-1) gi|8096552|dbj|AB043618.1| Babesia equi EMA-1 gene for merozoite antigen 1, complete cds
  • AB013725 (EMA-2) gi|3142236|dbj|AB013725.1| Babesia equi gene for merozoite antigen 2, complete cds

Eimeria maxima

  • AAO52676 (TFP250) gi|31322550|gb|AAO52676.1| TFP250 [Eimeria maxima]

Eimeria tenella

  • AJ306453 (MIC4) gi|187340650|emb|AJ306453.2| Eimeria tenella mRNA for microneme protein 4 (mic4 gene)
  • AJ245536 (MIC5) gi|5708121|emb|AJ245536.1| Eimeria tenella mRNA for microneme protein 5 (mic-5 gene)
  • AY566297 (ENR) gi|50295339|gb|AY566297.1| Eimeria tenella enoyl-acyl carrier reductase (ENR) mRNA, complete cds
  • Z71755 (MIC2) gi|209414697|emb|Z71755.2| Eimeria tenella mRNA for acidic microneme protein precursor, clone Etmic-2
  • AJ586535 (SAG4) gi|37699771|emb|AJ586535.1| Eimeria tenella mRNA for surface antigen 4 (sag4 gene)
  • AJ586537 (SAG8) gi|37699775|emb|AJ586537.1| Eimeria tenella mRNA for surface antigen 8 (sag8 gene)
  • AF353515 (Enolase) gi|13774514|gb|AF353515.1| Eimeria tenella enolase mRNA, complete cds
  • AF043910 (PYK) gi|2854032|gb|AF043910.1| Eimeria tenella pyruvate kinase (PYK) mRNA, complete cds

Babesia microti